Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC) (Q44624121)

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scientific article published on September 1, 2003

Language	Label	Description	Also known as
English	Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC)	scientific article published on September 1, 2003

Statements

scholarly article

1 reference

Europe PubMed Central

4 December 2017

Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC) (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14567627

23 March 2024

response elements

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14567627

23 March 2024

author name string

Young-Sam Keum

1

1 reference

Europe PubMed Central

4 December 2017

Bok-Ryang Kim

3

1 reference

Europe PubMed Central

4 December 2017

Rong Hu

4

1 reference

Europe PubMed Central

4 December 2017

Edward D. Owuor

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14567627

23 March 2024

A. N Tony Kong

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14567627

23 March 2024

language of work or name

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14567627

23 March 2024

publication date

1 September 2003

1 reference

Europe PubMed Central

4 December 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

4 December 2017

20

1 reference

Europe PubMed Central

4 December 2017

9

1 reference

Europe PubMed Central

4 December 2017

1351-1356

1 reference

Europe PubMed Central

4 December 2017

p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ARE- and TRE-mediated regulation of gene expression. Response to xenobiotics and antioxidants

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of gamma-glutamylcysteine synthetase heavy subunit gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of rat liver cytochrome P450 isozymes by isothiocyanates and their conjugates: a structure-activity relationship study

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the c-Jun N-terminal kinase/stress-activated protein kinase pathway by overexpression of caspase-8 and its homologs

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A review of mechanisms underlying anticarcinogenicity by brassica vegetables

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of cancer by isothiocyanates, modifiers of carcinogen metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox regulation of glutathione S-transferase induction by benzyl isothiocyanate: correlation of enzyme induction with the formation of reactive oxygen intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent induction of phase 2 enzymes in human prostate cells by sulforaphane

1 reference

https://pubmed.ncbi.nlm.nih.gov/14567627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1025737622815

1 reference

Europe PubMed Central

4 December 2017

1 reference

Europe PubMed Central

4 December 2017

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