Hypoxia upregulates von Hippel-Lindau tumor-suppressor protein through RhoA-dependent activity in renal cell carcinoma (Q44635423)

4 December 2017

Hypoxia upregulates von Hippel-Lindau tumor-suppressor protein through RhoA-dependent activity in renal cell carcinoma (English)

1 reference

4 December 2017

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1 reference

https://api.crossref.org/works/10.1152/AJPRENAL.00254.2003

26 March 2024

author name string

Sandra Turcotte

1

1 reference

4 December 2017

Richard Beliveau

3

1 reference

4 December 2017

Richard R. Desrosiers

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14583436

26 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14583436

26 March 2024

publication date

28 October 2003

1 reference

full work available at URL

4 December 2017

https://www.physiology.org/doi/pdf/10.1152/ajprenal.00254.2003

1 reference

https://api.crossref.org/works/10.1152/AJPRENAL.00254.2003

American Journal of Physiology - Renal Physiology

26 March 2024

published in

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4 December 2017

286

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4 December 2017

2

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4 December 2017

F338-48

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A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology

4 December 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Rho GTPases and their effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Human cytotrophoblast expression of the von Hippel-Lindau protein is downregulated during uterine invasion in situ and upregulated by hypoxia in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Rac1 activity is required for the activation of hypoxia-inducible factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Cytoskeletal changes in hypoxic pulmonary endothelial cells are dependent on MAPK-activated protein kinase MK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

The von Hippel-Lindau tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Small G-protein networks: their crosstalk and signal cascades.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

von Hippel-Lindau protein complex is regulated by cell density

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: specific nuclear localization of the B subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Interleukin-1 beta and reactive oxygen species mediate activation of c-Jun NH2-terminal kinases, in human epithelial cells, by two independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Rho-kinase regulates myosin II activation in MDCK cells during recovery after ATP depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Small GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

HIF-1α mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Purification and characterization of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00254.2003

Modeling ischemia in vitro: selective depletion of adenine and guanine nucleotide pools

21 January 2018

9

1 reference

https://api.crossref.org/works/10.1152/AJPRENAL.00254.2003

Rho GTPase signaling regulates tight junction assembly and protects tight junctions during ATP depletion

26 March 2024

12

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https://api.crossref.org/works/10.1152/AJPRENAL.00254.2003

26 March 2024

Identifiers

1 reference

4 December 2017

1 reference