The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosporylation of the Bcl-2 family member Bad. (Q44641896)

4 December 2017

title

The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosporylation of the Bcl-2 family member Bad. (English)

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4 December 2017

3

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4 December 2017

Anna Cartier

1

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4 December 2017

Tomoaki Komai

series ordinal

2

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4 December 2017

language of work or name

English

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publication date

1 November 2003

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Experimental Cell Research

4 December 2017

published in

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4 December 2017

volume

291

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4 December 2017

issue

1

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4 December 2017

page(s)

242-250

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4 December 2017

cites work

Viruses and apoptosis

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Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner

7 January 2021

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Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in HEp-2 cells

7 January 2021

1 reference

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The herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by the virus

7 January 2021

1 reference

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US3 protein kinase of herpes simplex virus type 2 plays a role in protecting corneal epithelial cells from apoptosis in infected mice

7 January 2021

1 reference

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Antiapoptotic activity of herpes simplex virus type 2: the role of US3 protein kinase gene

7 January 2021

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US3 protein kinase of herpes simplex virus protects primary afferent neurons from virus-induced apoptosis in ICR mice

7 January 2021

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Identification of the herpes simplex virus protein kinase as the product of viral gene US3.

7 January 2021

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Purification and biochemical characterization of the protein kinase encoded by the US3 gene of herpes simplex virus type 2.

7 January 2021

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Identification of a target protein of US3 protein kinase of herpes simplex virus type 2.

7 January 2021

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The US3 protein kinase of herpes simplex virus type 2 is associated with phosphorylation of the UL12 alkaline nuclease in vitro

7 January 2021

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Construction of a US3 lacZ insertion mutant of herpes simplex virus type 2 and characterization of its phenotype in vitro and in vivo

7 January 2021

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Virulence of and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1.

7 January 2021

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Immunohistochemical studies on the transneuronal spread of virulent herpes simplex virus type 2 and its US3 protein kinase-deficient mutant after ocular inoculation

7 January 2021

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The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage

7 January 2021

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

7 January 2021

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

7 January 2021

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

7 January 2021

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Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway

7 January 2021

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Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

7 January 2021

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Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

7 January 2021

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Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells

7 January 2021

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Quantitation of human immunodeficiency virus type 1 in the blood of infected persons

7 January 2021

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HSV and glycoprotein J inhibit caspase activation and apoptosis induced by granzyme B or Fas.

7 January 2021

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The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins

7 January 2021

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The herpes simplex virus-1 Us3 protein kinase blocks CD8T cell lysis by preventing the cleavage of Bid by granzyme B.

7 January 2021

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Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins

7 January 2021

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The substrate specificity of the protein kinase induced in cells infected with herpesviruses: studies with synthetic substrates [corrected] indicate structural requirements distinct from other protein kinases.

7 January 2021

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Further definition of the substrate specificity of the alpha-herpesvirus protein kinase and comparison with protein kinases A and C

7 January 2021

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Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-4827(03)00375-6

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4 December 2017

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