The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice. (Q44645827)

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20 December 2019

title

The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice (English)

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20 December 2019

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4

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20 December 2019

Alasdair M Barr

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20 December 2019

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Marc G Caron

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20 December 2019

author name string

Virginia Lehmann-Masten

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20 December 2019

Martin Paulus

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20 December 2019

Mark A Geyer

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language of work or name

English

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publication date

1 February 2004

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20 December 2019

published in

Neuropsychopharmacology

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20 December 2019

volume

29

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20 December 2019

issue

2

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20 December 2019

page(s)

221-228

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1300343

20 December 2019

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cites work

Serotonin and Hallucinogens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Serotonin model of schizophrenia: emerging role of glutamate mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Positron emission tomographic analysis of dose-dependent MDL 100,907 binding to 5-hydroxytryptamine-2A receptors in the human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

A systematic review of the use of atypical antipsychotics in autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Distribution of serotonin 5-HT(2A) receptors in afferents of the rat striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Functional hyperdopaminergia in dopamine transporter knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Monoamine transporter pharmacology and mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Behavioral studies of hallucinogenic drugs in animals: implications for schizophrenia research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Alterations in the cortical serotonergic system in schizophrenia: a postmortem study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Molecular, pharmacological and functional diversity of 5-HT receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Classification and nomenclature of 5-HT receptors: a comment on current issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Polymorphism of the serotonin-2A receptor gene (HTR2A) associated with childhood attention deficit hyperactivity disorder (ADHD) in adult women with seasonal affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

5-HT(2A) receptor antagonism potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and inhibits that in the nucleus accumbens in a dose-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Role of striatal serotonin2A and serotonin2C receptor subtypes in the control of in vivo dopamine outflow in the rat striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

The role of serotonin in antipsychotic drug action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Reversal of amphetamine-induced behaviours by MDL 100,907, a selective 5-HT2A antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

5-HT2 receptor antagonism reduces hyperactivity induced by amphetamine, cocaine, and MK-801 but not D1 agonist C-APB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

5-HT modulation of auditory and visual sensorimotor gating: II. Effects of the 5-HT2A antagonist MDL 100,907 on disruption of sound and light prepulse inhibition produced by 5-HT agonists in Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Electrophysiological, biochemical and behavioral evidence for 5-HT2 and 5-HT3 mediated control of dopaminergic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

A temporal and spatial scaling hypothesis for the behavioral effects of psychostimulants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

M100,907, a selective 5-HT(2A) antagonist, attenuates dopamine release in the rat medial prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Sensorimotor gating deficits in bipolar disorder patients with acute psychotic mania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Atypical antipsychotics: are some more atypical than others?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Pharmacological and molecular targets in the search for novel antipsychotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

DOI disrupts prepulse inhibition of startle in rats via 5-HT2A receptors in the ventral pallidum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Behavioural disturbances associated with hyperdopaminergia in dopamine-transporter knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

M100907, a serotonin 5-HT2A receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Antagonism at 5-HT(2A) receptors potentiates the effect of haloperidol in a conditioned avoidance response task in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Enhancement of antipsychoticlike properties of raclopride in rats using the selective serotonin2A receptor antagonist MDL 100,907.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

The selective 5-HT2A receptor antagonist MDL 100,907 counteracts the psychomotor stimulation ensuing manipulations with monoaminergic, glutamatergic or muscarinic neurotransmission in the mouse--implications for psychosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

7 January 2021

The role of endogenous sensitization in the pathophysiology of schizophrenia: implications from recent brain imaging studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

7 January 2021

Effects of atypical antipsychotic drugs on dopamine output in the shell and core of the nucleus accumbens: role of 5-HT(2A) and alpha(1)-adrenoceptor antagonism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

7 January 2021

Decreased serotonin 2A receptor densities in neuroleptic-naive patients with schizophrenia: A PET study using [(18)F]setoperone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

7 January 2021

The role of positron emission tomography in the drug development of M100907, a putative antipsychotic with a novel mechanism of action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

7 January 2021

Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

7 January 2021

The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

7 January 2021

Serotonin-2A receptor gene is not associated with symptomatology of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

7 January 2021

High 5HT2A receptor occupancy in M100907-treated schizophrenic patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300343

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1300343

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14603268%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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