Molecular model of the neural dopamine transporter (Q44667602)

5 December 2017

title

Molecular model of the neural dopamine transporter (English)

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5 December 2017

2

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5 December 2017

Aina Westrheim Ravna

1

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5 December 2017

Svein G Dahl

series ordinal

3

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5 December 2017

publication date

1 May 2003

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5 December 2017

number of pages

16

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Journal of Computer - Aided Molecular Design

inferred from page(s)

published in

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5 December 2017

volume

17

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5 December 2017

issue

5-6

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5 December 2017

page(s)

367-382

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Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression.

5 December 2017

cites work

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Comparison of the release of [3H]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine.

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High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol

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The Protein Data Bank

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12 December 2020

Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter

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12 December 2020

Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants

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12 December 2020

A putative model of the dopamine transporter.

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12 December 2020

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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12 December 2020

Improved tools for biological sequence comparison

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12 December 2020

Mutational analysis of amiloride sensitivity of the NhaA Na+/H+ antiporter from Vibrio parahaemolyticus

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12 December 2020

Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

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12 December 2020

Transport-dependent accessibility of a cytoplasmic loop cysteine in the human dopamine transporter

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12 December 2020

From membrane to molecule to the third amino acid from the left with a membrane transport protein

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12 December 2020

A point mutation (G338S) and its suppressor mutations affect both the pH response of the NhaA-Na+/H+ antiporter as well as the growth phenotype of Escherichia coli

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12 December 2020

Synthesis, ligand binding, QSAR, and CoMFA study of 3 beta-(p-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters

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12 December 2020

Tyrosine-533 of rat dopamine transporter: involvement in interactions with 1-methyl-4-phenylpyridinium and cocaine

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12 December 2020

Permeation and gating residues in serotonin transporter

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12 December 2020

Crystal structure of bacterial multidrug efflux transporter AcrB

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12 December 2020

The membrane topology of GAT-1, a (Na+ + Cl-)-coupled gamma-aminobutyric acid transporter from rat brain

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12 December 2020

Dopamine transporter mutants, small molecules, and approaches to cocaine antagonist/dopamine transporter disinhibitor development.

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12 December 2020

Determination of external loop topology in the serotonin transporter by site-directed chemical labeling

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12 December 2020

Molecular model of the Escherichia coli Na1/H1 antiporter NhaA.

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12 December 2020

Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding

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12 December 2020

Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter.

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12 December 2020

Chemical release of dopamine from striatal homogenates: evidence for an exchange diffusion model

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12 December 2020

A functional superfamily of sodium/solute symporters

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12 December 2020

The role of external loop regions in serotonin transport. Loop scanning mutagenesis of the serotonin transporter external domain

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12 December 2020

Essential aspartic acid residues, Asp-133, Asp-163 and Asp-164, in the transmembrane helices of a Na+/H+ antiporter (NhaA) from Escherichia coli

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12 December 2020

Proposed structure of putative glucose channel in GLUT1 facilitative glucose transporter

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12 December 2020

Three-dimensional structure of the ion-coupled transport protein NhaA.

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12 December 2020

Dissection of dopamine and cocaine binding sites on the rat dopamine transporter expressed in COS cells

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12 December 2020

Topological analysis of NhaA, a Na+/H+ antiporter from Escherichia coli.

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12 December 2020

A functional-phylogenetic classification system for transmembrane solute transporters

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12 December 2020

Three-dimensional structure of a bacterial oxalate transporter.

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12 December 2020

Molecular mechanics calculations of proteins. Comparison of different energy minimization strategies.

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12 December 2020

A putative three-dimensional arrangement of the human serotonin transporter transmembrane helices: a tool to aid experimental studies

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12 December 2020

Molecular construction of a multidrug exporter system, AcrAB: molecular interaction between AcrA and AcrB, and cleavage of the N-terminal signal sequence of AcrA.

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12 December 2020

Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells.

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12 December 2020

Oligomerization of serotonin transporter and its functional consequences

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12 December 2020

Ab InitioModeling and Molecular Dynamics Simulation of the α1b-Adrenergic Receptor Activation

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Analysis of the transmembrane topology of the glycine transporter GLYT1

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12 December 2020

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12 December 2020

Topological localization of cysteine 74 in the GABA transporter, GAT1, and its importance in ion binding and permeation.

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12 December 2020

The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter

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12 December 2020

Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment

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12 December 2020

PHD: predicting one-dimensional protein structure by profile-based neural networks

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12 December 2020

Possible existence of quaternary structure in the high-affinity serotonin transport complex.

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12 December 2020

The rat serotonin transporter: identification of cysteine residues important for substrate transport

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12 December 2020

Dopamine transporter: transmembrane phenylalanine mutations can selectively influence dopamine uptake and cocaine analog recognition.

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12 December 2020

Crystal structure of a bacterial cocaine esterase

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12 December 2020

The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding

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12 December 2020

A single serine residue controls the cation dependence of substrate transport by the rat serotonin transporter

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12 December 2020

Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter

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12 December 2020

Dopamine transporter mutants selectively enhance MPP+ transport

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12 December 2020

A pH-dependent conformational change of NhaA Na(+)/H(+) antiporter of Escherichia coli involves loop VIII-IX, plays a role in the pH response of the protein, and is maintained by the pure protein in dodecyl maltoside

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12 December 2020

A World Wide Web-service to aid the development of AMBER parameters using analogy to standard parameters

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12 December 2020

Identification of tryptophan residues critical for the function and targeting of the gamma-aminobutyric acid transporter (subtype A).

1 reference

12 December 2020

Cysteine-scanning mutagenesis of transmembrane segment 11 of the GLUT1 facilitative glucose transporter.

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12 December 2020

RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

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12 December 2020

Identification and characterization of functional residues in a Na+/H+ antiporter (NhaA) from Escherichia coli by random mutagenesis.

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12 December 2020

Model of the 3-D structure of the GLUT3 glucose transporter and molecular dynamics simulation of glucose transport

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12 December 2020

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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12 December 2020

Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter.

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12 December 2020

Ligand induced conformational states of the 5-HT(1A) receptor

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12 December 2020

Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.

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12 December 2020

Histidine-226 is part of the pH sensor of NhaA, a Na+/H+ antiporter in Escherichia coli.

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12 December 2020

Ligand interaction with the purified serotonin transporter in solution and at the air/water interface

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12 December 2020

Histidine 225, a residue of the NhaA-Na+/H+ antiporter of Escherichia coli is exposed and faces the cell exterior

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12 December 2020

Importance of valine at position 152 for the substrate transport and 2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane binding of dopamine transporter.

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12 December 2020

Identifiers

DOI

10.1023/A:1026116017725

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5 December 2017

DBLP publication ID

journals/jcamd/RavnaSD03

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DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

1002893493

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