Factor Va is inactivated by activated protein C in the absence of cleavage sites at Arg-306, Arg-506, and Arg-679. (Q44683596)

5 December 2017

title

Factor Va is inactivated by activated protein C in the absence of cleavage sites at Arg-306, Arg-506, and Arg-679. (English)

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5 December 2017

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Marijn van der Neut Kolfschoten

1

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5 December 2017

Richard J Dirven

2

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5 December 2017

Hans L Vos

3

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5 December 2017

Guido Tans

4

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5 December 2017

Jan Rosing

5

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5 December 2017

Rogier M Bertina

6

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5 December 2017

language of work or name

English

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publication date

2 December 2003

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Journal of Biological Chemistry

5 December 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

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5 December 2017

volume

279

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5 December 2017

issue

8

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5 December 2017

page(s)

6567-6575

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https://api.crossref.org/works/10.1074%2FJBC.M308574200

5 December 2017

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Kinetic studies of prothrombin activation: effect of factor Va and phospholipids on the formation of the enzyme-substrate complex

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1 reference

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Regulation of blood coagulation

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Deficiency of protein C in congenital thrombotic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Familial protein S deficiency is associated with recurrent thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Mutation in blood coagulation factor V associated with resistance to activated protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

World distribution of factor V Leiden

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Factor V Arg306-->Thr (factor V Cambridge) and factor V Arg306-->Gly mutations in venous thrombotic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Importance of individual activated protein C cleavage site regions in coagulation factor V for factor Va inactivation and for factor Xa activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

The activated protein C (APC)-resistant phenotype of APC cleavage site mutants of recombinant factor V in a reconstituted plasma model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Functional characterization of recombinant FV Hong Kong and FV Cambridge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Peptide Bond Cleavages and Loss of Functional Activity during Inactivation of Factor Va and Factor VaR506Q by Activated Protein C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Importance of protein S and phospholipid for activated protein C-mediated cleavages in factor Va.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Binding sites for blood coagulation factor Xa and protein S involving residues 493-506 in factor Va.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

The effect of Arg306-->Ala and Arg506-->Gln substitutions in the inactivation of recombinant human factor Va by activated protein C and protein S.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Association of idiopathic venous thromboembolism with single point-mutation at Arg506 of factor V

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men

21 January 2018

1 reference

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The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

The effect of phospholipids, calcium ions and protein S on rate constants of human factor Va inactivation by activated human protein C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Vectors used for expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Protein C activation and factor Va inactivation on human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Activated protein C cleavage of factor Va leads to dissociation of the A2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

Expression and characterization of recombinant human factor V and a mutant lacking a major portion of the connecting region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308574200

21 January 2018

Identifiers

DOI

10.1074/JBC.M308574200

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5 December 2017

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