Hormesis: its impact on medicine and health (Q44693677)

5 December 2017

title

Hormesis: its impact on medicine and health (English)

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5 December 2017

2

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5 December 2017

E J Calabrese

1

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5 December 2017

V Calabrese

series ordinal

3

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5 December 2017

publication date

11 October 2012

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Human & Experimental Toxicology

5 December 2017

published in

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5 December 2017

volume

32

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5 December 2017

issue

2

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5 December 2017

page(s)

120-152

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Hormesis. A Revolution in Biology, Toxicology and Medicine

5 December 2017

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Hormesis. Sipping from a poisoned chalice.

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Toxicology rethinks its central belief

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Hormesis: why it is important to toxicology and toxicologists

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Hormesis: why it is important to biogerontologists

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Hormesis and high-risk groups.

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Toxicology rewrites its history and rethinks its future: giving equal focus to both harmful and beneficial effects

21 January 2018

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Evidence that hormesis represents an "overcompensation" response to a disruption in homeostasis.

21 January 2018

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Hormesis--the stimulation of growth by low levels of inhibitors

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A theory for growth hormesis.

21 January 2018

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Overcompensation stimulation: a mechanism for hormetic effects

21 January 2018

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The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: an overview

21 January 2018

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The principles of bacteriology

21 January 2018

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Emotionality and the Yerkes-Dodson law.

21 January 2018

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Stress biology and hormesis: the Yerkes-Dodson law in psychology--a special case of the hormesis dose response

21 January 2018

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Converging concepts: adaptive response, preconditioning, and the Yerkes-Dodson Law are manifestations of hormesis

21 January 2018

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Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

21 January 2018

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Radiation hormesis: its historical foundations as a biological hypothesis

21 January 2018

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Radiation hormesis: the demise of a legitimate hypothesis

21 January 2018

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21 January 2018

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Hormesis: from marginalization to mainstream

21 January 2018

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Toxicological awakenings: the rebirth of hormesis as a central pillar of toxicology

21 January 2018

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Getting the dose-response wrong: why hormesis became marginalized and the threshold model accepted

21 January 2018

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Lower efficacy: interaction with an inhibitory receptor or partial agonism?

21 January 2018

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Bell-shaped curves for prostaglandin-induced modulation of adenylate cyclase: two mutually opposing effects

21 January 2018

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Hormesis: U-shaped dose responses and their centrality in toxicology

21 January 2018

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Adenosine: biphasic dose responses

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327112455069

Adrenergic receptors: biphasic dose responses

21 January 2018

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21 January 2018

Peptides and hormesis

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Chronic corticosterone administration dose-dependently modulates Abeta(1-42)- and NMDA-induced neurodegeneration in rat magnocellular nucleus basalis

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327112455069

Dopamine: biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Characterisation of endothelin induced relaxation in guinea-pig airways: evidence for dilatory ETA- and ETB-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Cancer biology and hormesis: human tumor cell lines commonly display hormetic (biphasic) dose responses

21 January 2018

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21 January 2018

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Biphasic estrogen response on bovine adrenal medulla capillary endothelial cell adhesion, proliferation and tube formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

5-Hydroxytryptamine (serotonin): biphasic dose responses

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327112455069

Opiates: biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Opioids regulate the release of human chorionic gonadotropin hormone from trophoblast tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Pharmacological enhancement of neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Nitric oxide: biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Effect of stem cell factor, interleukin-6, nitric oxide and transforming growth factor-beta on the osteoclast differentiation induced by 1 alpha,25-(OH)2D3 in primary murine bone marrow cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

N-methyl-D-aspartate receptors influence neuronal survival in developing spinal cord cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Androgens: biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Prostaglandins: biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Spermine promotes the survival of primary cultured brain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The role of MAPK in the biphasic dose-response phenomenon induced by cadmium and mercury in HEK293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Steroid receptors, and the generation of closely coupled/biphasic dose-response curves

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor

21 January 2018

1 reference

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Antiapoptotic and cytotoxic properties of delta opioid peptide [D-Ala(2),D-Leu(5)]enkephalin in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Estrogen regulation of in vitro brain tyrosine hydroxylase activity in the catfish Heteropneustes fossilis: interactions with cAMP-protein kinase A and protein kinase C systems in enzyme activation

21 January 2018

1 reference

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15-Deoxy-delta12,14-prostaglandin J2, a neuroprotectant or a neurotoxicant?

21 January 2018

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An assessment of anxiolytic drug screening tests: hormetic dose responses predominate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Modulation of the epileptic seizure threshold: implications of biphasic dose responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Stressor-specific enhancement of hsp induction by low doses of stressors in conditions of self- and cross-sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Evaluating homeopathic drugs within a biomedical framework.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Hormesis and its relationship with homeopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The reaction between acetyl choline and muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

STUDIES IN PROTOPLASM POISONING : I. PHENOLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

QUANTITATIVE RELATIONSHIPS BETWEEN THE IMMUNIZING DOSE OF EPIDEMIC INFLUENZA VIRUS AND THE RESULTANT IMMUNITY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Resveratrol commonly displays hormesis: occurrence and biomedical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Hormesis and plant biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Hormesis is central to toxicology, pharmacology and risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Low-level light stimulates excisional wound healing in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Hormetic dose-response relationships in immunology: occurrence, quantitative features of the dose response, mechanistic foundations, and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Chemotherapeutics and hormesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

A perspective on the scientific, philosophical, and policy dimensions of hormesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The hormetic morphogen theory of curvature and the morphogenesis and pathology of tubular and other curved structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Modulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell type

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Enhancement of HIV infection by cellulose sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Isoform-specific stimulation of cardiac Na/K pumps by nanomolar concentrations of glycosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Ouabain- and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Drug therapies for stroke and traumatic brain injury often display U-shaped dose responses: occurrence, mechanisms, and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The frequency of U-shaped dose responses in the toxicological literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Clinical application of ischemic preconditioning in the elderly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Hormesis can and does work in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Potential relevance of bell-shaped and u-shaped dose-responses for the therapeutic targeting of angiogenesis in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The emerging low-dose therapy for advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Mimetics of hormetic agents: stress-resistance triggers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Radiation hormesis: the good, the bad, and the ugly

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Evidence for hormesis in mutagenicity dose-response relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

In vivo mutagenic effect of very low dose radiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The PKZ1 recombination mutation assay: a sensitive assay for low dose studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Substance P increases neutrophil adhesion to human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Extremely low doses of X-radiation can induce adaptive responses in mouse prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The linear no-threshold model does not hold for low-dose ionizing radiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Predicting Low Dose Effects for Chemicals in High Through-Put Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The future of hormesis: where do we go from here?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The marginalization of hormesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Chemical hormesis: its historical foundations as a biological hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Characterization of U-101017 as a GABA(A) receptor ligand of dual functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Piperazine imidazo[1,5-a]quinoxaline ureas as high-affinity GABAA ligands of dual functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

High-affinity partial agonist imidazo[1,5-a]quinoxaline amides, carbamates, and ureas at the gamma-aminobutyric acid A/benzodiazepine receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

3-Phenyl-substituted imidazo[1,5-alpha]quinoxalin-4-ones and imidazo[1,5-alpha]quinoxaline ureas that have high affinity at the GABAA/benzodiazepine receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Hormesis in mixtures -- can it be predicted?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Cholinergic receptor interactions and their effects on long-term memory processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Memory enhancement: supra-additive effect of subcutaneous cholinergic drug combinations in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Two-drug combinations of memory enhancers: Effect of dose ratio upon potency and therapeutic window, in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Amnesia-reversal activity of a series of cyclic imides

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Hormesis provides a generalized quantitative estimate of biological plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Tumor resistance explained by hormesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Quantification of hormesis in anticancer-agent dose-responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

P-glycoprotein efflux transporter activity often displays biphasic dose-response relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Effect of pretreatment of rats with carbon tetrachloride on tolerance development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Carbon tetrachloride-induced protection against carbon tetrachloride toxicity. The role of the liver microsomal drug-metabolizing system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Reversibility of liver damage in rats rendered resistant to carbon tetrachloride by prior carbon tetrachloride administration: Bearing on the lipoperoxidation hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

A new pathway for DNA repair in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Is warm-up in angina ischaemic preconditioning?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Antigen-induced in vitro antibody production in humans: a model for B cell activation and immunoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

An elderly patient with fluoroquinolone-associated achilles tendinitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Safety profile of the fluoroquinolones: focus on levofloxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

In Vitro Discrimination of Fluoroquinolones Toxicity on Tendon Cells: Involvement of Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

A new gaseous signaling molecule emerges: cardioprotective role of hydrogen sulfide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Endocannabinoids, FOXO and the metabolic syndrome: redox, function and tipping point--the view from two systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Effects of low doses of dietary lead on puberty onset in female mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Low doses of dietary lead are associated with a profound reduction in the time to the onset of puberty in female mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Paradigm lost, paradigm found: the re-emergence of hormesis as a fundamental dose response model in the toxicological sciences

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

Response of Fetal Rabbit Ductus Arteriosus to Bradykinin: Role of Nitric Oxide, Prostaglandins, and Bradykinin Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327112455069

The Historical Aspect of Quackery

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1136/BMJ.2.3482.589

22 August 2022

Identifiers

DOI

10.1177/0960327112455069

1 reference

5 December 2017

1 reference