Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: preliminary results of a phase I trial in patients with recurrent malignant gliomas. (Q44697885)

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scientific article published in December 2003

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English	Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: preliminary results of a phase I trial in patients with recurrent malignant gliomas.	scientific article published in December 2003

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scholarly article

1 reference

Europe PubMed Central

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16 November 2019

Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: preliminary results of a phase I trial in patients with recurrent malignant gliomas (English)

1 reference

Europe PubMed Central

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16 November 2019

phase I clinical trial

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1 reference

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Isabelle M. Germano

1

1 reference

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16 November 2019

author name string

Jennifer Fable

2

1 reference

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16 November 2019

S Humayun Gultekin

3

1 reference

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16 November 2019

Adam Silvers

4

1 reference

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16 November 2019

publication date

1 December 2003

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16 November 2019

Journal of Neuro-Oncology

1 reference

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16 November 2019

65

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16 November 2019

3

1 reference

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16 November 2019

279-289

1 reference

Europe PubMed Central

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16 November 2019

https://scigraph.springernature.com/pub.10.1023/b:neon.0000003657.95085.56

0 references

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase II study of temozolomide in patients with newly diagnosed supratentorial malignant glioma before radiation therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenoviral-mediated thymidine kinase gene transfer into the primate brain followed by systemic ganciclovir: pathologic, radiologic, and molecular studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical use of the optical digitizer for intracranial neuronavigation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracranial administration of adenovirus expressing HSV-TK in combination with ganciclovir produces a dose-dependent, self-limiting inflammatory response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir treatment of life- or sight-threatening cytomegalovirus infection: experience in 314 immunocompromised patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An experimental model of retrovirus gene therapy for malignant brain tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfer of a foreign gene into the brain using adenovirus vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human gene marker/therapy clinical protocols

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of primary brain tumors: current concepts and review of the literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional and Transforming Activities of the Adenovirus E1A Proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of progressive or recurrent pediatric malignant supratentorial brain tumors with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell kinetic analyses of human malignant brain tumors (gliomas)

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated gene therapy of experimental gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated gene therapy for experimental spinal cord tumors: tumoricidal efficacy and functional outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute neurologic dysfunction associated with high-dose chemotherapy and autologous bone marrow rescue for primary malignant brain tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus vectors enter the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncolytic viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An adenovirus vector for gene transfer into neurons and glia in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirally mediated gene transfer into experimental solid brain tumors and leptomeningeal cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serial MR in gene therapy for recurrent glioblastoma: initial experience and work in progress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotherapy of brain tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene stereotactic neurosurgery for recurrent malignant gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer surveillance series [corrected]: brain and other central nervous system cancers: recent trends in incidence and mortality.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early postoperative magnetic resonance imaging after resection of malignant glioma: objective evaluation of residual tumor and its influence on regrowth and prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrovirus-mediated gene therapy of experimental brain neoplasms using the herpes simplex virus-thymidine kinase/ganciclovir paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term rat survival after malignant brain tumor regression by retroviral gene therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of intracerebral injection of a replication-defective adenoviral vector in a semipermissive species (cotton rat).

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of factors predicting accurate resection of high-grade gliomas by using frameless image-guided stereotactic guidance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of multiple lesions during radiation therapy and chemotherapy in patients with gliomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for construction of adenovirus vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRI characteristics and histological changes in glioblastoma after gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of adenovirus type 11 from the brain of a neonate with pneumonia and encephalitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of human serum and cerebrospinal fluid on retroviral vectors and packaging cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus vectors to transfer genes into neurones: implications for gene therapy of neurological disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidine kinase-mediated killing of rat brain tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14682378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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