A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain (Q44711807)

5 December 2017

A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain (English)

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5 December 2017

7

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5 December 2017

Patrick C Reid

1

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5 December 2017

Naomi Sakashita

2

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5 December 2017

Shigeki Sugii

3

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5 December 2017

Yoshiko Ohno-Iwashita

4

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5 December 2017

Yukiko Shimada

5

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5 December 2017

William F Hickey

6

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5 December 2017

1 January 2004

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Journal of Lipid Research

5 December 2017

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5 December 2017

45

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5 December 2017

3

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5 December 2017

582-591

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Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

5 December 2017

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Cessation of rapid late endosomal tubulovesicular trafficking in Niemann-Pick type C1 disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Trafficking of cholesterol from cell bodies to distal axons in Niemann Pick C1-deficient neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemann-Pick type C1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Niemann-Pick type C mutations cause lipid traffic jam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Transmembrane molecular pump activity of Niemann-Pick C1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Identification of HE1 as the second gene of Niemann-Pick C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Lipid changes in Niemann-Pick disease type C brain: personal experience and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Neurons in Niemann-Pick disease type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Critical role for glycosphingolipids in Niemann-Pick disease type C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Spatial and temporal distribution of intracellular free cholesterol in brains of a Niemann-Pick type C mouse model showing hyperphosphorylated tau protein. Implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Neurodegeneration in Niemann-Pick type C disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts).

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Biotinylated theta-toxin derivative as a probe to examine intracellular cholesterol-rich domains in normal and Niemann-Pick type C1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Sites and temporal changes of gangliosides GM1/GM2 storage in the Niemann-Pick disease type C mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Cholesterol accumulation in NPC1-deficient neurons is ganglioside dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann-Pick C1-deficient neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Regional distribution of NPC1 protein in monkey brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Degeneration of neurons and glia in the Niemann-Pick C mouse is unrelated to the low-density lipoprotein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

CNS synaptogenesis promoted by glia-derived cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Functional rafts in cell membranes

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Functions of lipid rafts in biological membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Jamming the endosomal system: lipid rafts and lysosomal storage diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Posttranslational regulation of acid sphingomyelinase in niemann-pick type C1 fibroblasts and free cholesterol-enriched chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

Fate of Endogenously Synthesized Cholesterol in Niemann-Pick Type C1 Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.D300032-JLR200

10.1194/JLR.D300032-JLR200

21 January 2018

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DOI

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5 December 2017

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