HIV-1 Nef perturbs the function, structure, and signaling of the Golgi through the Src kinase Hck. (Q44715005)

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31 January 2020

title

HIV-1 Nef perturbs the function, structure, and signaling of the Golgi through the Src kinase Hck (English)

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7

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Shinya Suzu

9

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author name string

Masateru Hiyoshi

1

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31 January 2020

Naoko Takahashi-Makise

2

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Yuka Yoshidomi

3

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Nopporn Chutiwitoonchai

4

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Takashi Chihara

5

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Masato Okada

6

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Seiji Okada

8

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publication date

1 March 2012

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Journal of Cellular Physiology

31 January 2020

published in

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volume

227

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issue

3

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page(s)

1090-1097

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Src regulates Golgi structure and KDEL receptor-dependent retrograde transport to the endoplasmic reticulum

31 January 2020

cites work

1 reference

Mapping the interaction between GRASP65 and GM130, components of a protein complex involved in the stacking of Golgi cisternae

21 January 2018

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Identification and characterization of golgin-84, a novel Golgi integral membrane protein with a cytoplasmic coiled-coil domain

21 January 2018

1 reference

ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65.

21 January 2018

1 reference

Alterations in pp60c-src accompany differentiation of neurons from rat embryo striatum

21 January 2018

1 reference

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

21 January 2018

1 reference

The role of GRASP55 in Golgi fragmentation and entry of cells into mitosis

21 January 2018

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GRASP55 regulates Golgi ribbon formation

21 January 2018

1 reference

HIV-1 Nef: at the crossroads

21 January 2018

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Structure--function relationships in HIV-1 Nef.

21 January 2018

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Regulation of O-glycosylation through Golgi-to-ER relocation of initiation enzymes

21 January 2018

1 reference

Hematopoietic cell kinase (Hck) isoforms and phagocyte duties - from signaling and actin reorganization to migration and phagocytosis

21 January 2018

1 reference

Colony-stimulating factors in inflammation and autoimmunity.

21 January 2018

1 reference

The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.

21 January 2018

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Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms.

21 January 2018

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Interaction between Hck and HIV-1 Nef negatively regulates cell surface expression of M-CSF receptor.

21 January 2018

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HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I.

21 January 2018

1 reference

Activation of the MAPK module from different spatial locations generates distinct system outputs

21 January 2018

1 reference

Identification and characterization of a novel Golgi protein, golgin-67.

21 January 2018

1 reference

Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome

21 January 2018

1 reference

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

21 January 2018

1 reference

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

21 January 2018

1 reference

Assembly of asparagine-linked oligosaccharides

21 January 2018

1 reference

Constitutive activation of neuronal Src causes aberrant dendritic morphogenesis in mouse cerebellar Purkinje cells.

21 January 2018

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Src-family kinases: rheostats of immune cell signaling

21 January 2018

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HIV-1 accessory proteins--ensuring viral survival in a hostile environment

21 January 2018

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The biogenesis of the Golgi ribbon: the roles of membrane input from the ER and of GM130.

21 January 2018

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Involvement of Golgi-associated Lyn tyrosine kinase in the translocation of annexin II to the endoplasmic reticulum under oxidative stress.

21 January 2018

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Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

21 January 2018

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A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway.

21 January 2018

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GM130 and GRASP65-dependent lateral cisternal fusion allows uniform Golgi-enzyme distribution

21 January 2018

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Coordination of the secretory compartments via inter-organelle signalling

21 January 2018

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Golgi dysfunction is a common feature in idiopathic human pulmonary hypertension and vascular lesions in SHIV-nef-infected macaques.

21 January 2018

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Fragmentation and dispersal of the pericentriolar Golgi complex is required for entry into mitosis in mammalian cells

21 January 2018

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p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction

21 January 2018

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HIV-1 Nef interferes with M-CSF receptor signaling through Hck activation and inhibits M-CSF bioactivities.

21 January 2018

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HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction

21 January 2018

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Allosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor

21 January 2018

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A direct role for GRASP65 as a mitotically regulated Golgi stacking factor

21 January 2018

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Src kinase regulates the integrity and function of the Golgi apparatus via activation of dynamin 2

21 January 2018

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GRASP55 and GRASP65 play complementary and essential roles in Golgi cisternal stacking

21 January 2018

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Golgi retention mechanism of beta-1,4-galactosyltransferase. Membrane-spanning domain-dependent homodimerization and association with alpha- and beta-tubulins

21 January 2018

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Convergence of cell cycle regulation and growth factor signals on GRASP65

21 January 2018

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Lack of Palmitoylation Redirects p59Hckfrom the Plasma Membrane to p61Hck-positive Lysosomes

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCP.22825

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31 January 2020

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