Impaired immune responses and altered peptide repertoire in tapasin-deficient mice (Q44715940)

5 December 2017

Impaired immune responses and altered peptide repertoire in tapasin-deficient mice (English)

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5 December 2017

Garbi N

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5 December 2017

Tan P

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5 December 2017

Diehl AD

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5 December 2017

Chambers BJ

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5 December 2017

Ljunggren HG

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5 December 2017

Momburg F

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Hämmerling GJ

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5 December 2017

language of work or name

English

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publication date

1 September 2000

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5 December 2017

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3

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234-238

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Generation and TAP-mediated transport of peptides for major histocompatibility complex class I molecules.

5 December 2017

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7 January 2021

Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP

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7 January 2021

ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly

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7 January 2021

A role for the thiol-dependent reductase ERp57 in the assembly of MHC class I molecules

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7 January 2021

The thiol oxidoreductase ERp57 is a component of the MHC class I peptide-loading complex.

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7 January 2021

Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC

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7 January 2021

Sequence, linkage to H2-K, and function of mouse tapasin in MHC class I assembly

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7 January 2021

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

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7 January 2021

Dependence of peptide binding by MHC class I molecules on their interaction with TAP.

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7 January 2021

HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading.

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7 January 2021

Retention of empty MHC class I molecules by tapasin is essential to reconstitute antigen presentation in invertebrate cells

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7 January 2021

Tapasin enhances assembly of transporters associated with antigen processing-dependent and -independent peptides with HLA-A2 and HLA-B27 expressed in insect cells

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7 January 2021

Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line .220.

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7 January 2021

Elucidation of the genetic basis of the antigen presentation defects in the mutant cell line .220 reveals polymorphism and alternative splicing of the tapasin gene

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7 January 2021

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

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7 January 2021

Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells.

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7 January 2021

Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

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7 January 2021

Induction of peripheral CD8+ T-cell tolerance by cross-presentation of self antigens

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7 January 2021

Empty MHC class I molecules come out in the cold

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7 January 2021

Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro.

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7 January 2021

Cooperative interaction of B lymphocytes with antigen-specific helper T lymphocytes is MHC restricted

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7 January 2021

Surface appearance and instability of empty H-2 class I molecules under physiological conditions

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7 January 2021

The fate of the three subunits of major histocompatibility complex class I molecules

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7 January 2021

TAP2-defective RMA-S cells present Sendai virus antigen to cytotoxic T lymphocytes

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7 January 2021

MHC class I molecules form ternary complexes with calnexin and TAP and undergo peptide-regulated interaction with TAP via their extracellular domains

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7 January 2021

Positive selection of self- and alloreactive CD8+ T cells in Tap-1 mutant mice.

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7 January 2021

TAP1-deficient mice select a CD8+ T cell repertoire that displays both diversity and peptide specificity

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7 January 2021

Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses

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7 January 2021

How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?

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7 January 2021

The impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II molecules

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7 January 2021

Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions.

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7 January 2021

A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules.

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7 January 2021

Triggering of natural killer cells by the costimulatory molecule CD80 (B7-1)

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7 January 2021

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

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7 January 2021

LacZ inducible, antigen/MHC-specific T cell hybrids

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7 January 2021

Altered natural killer cell repertoire in Tap-1 mutant mice

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7 January 2021

Identifiers

DOI

10.1038/79775

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5 December 2017

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