Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. (Q44777514)

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scientific article published in February 2004

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English	Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.	scientific article published in February 2004

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scholarly article

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24 November 2019

Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease (English)

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24 November 2019

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Parkinson's disease

1 reference

based on heuristic

inferred from title

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based on heuristic

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based on heuristic

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Yoshikuni Mizuno

7

object named as

Yoshikuni Mizuno

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6 December 2017

author name string

Tsuyoshi Furuya

1

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24 November 2019

Hideki Hayakawa

2

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24 November 2019

Masanori Yamada

3

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24 November 2019

Kenji Yoshimi

4

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24 November 2019

Shin Hisahara

5

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24 November 2019

Masayuki Miura

6

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24 November 2019

Hideki Mochizuki

8

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24 November 2019

Yoshikuni Mizuno

7

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publication date

1 February 2004

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24 November 2019

Journal of Neuroscience

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24 November 2019

24

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24 November 2019

8

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24 November 2019

1865-1872

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24 November 2019

Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

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Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

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Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual role of inflammatory stimuli in activation-induced cell death of mouse microglial cells. Initiation of two separate apoptotic pathways via induction of interferon regulatory factor-1 and caspase-11.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct downstream pathways of caspase-11 in regulating apoptosis and cytokine maturation during septic shock response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroinflammatory processes in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HPLC-assay with electrochemical detection for the neurotoxin MPTP, its metabolite MPP+ and MPTP-analogues in biological samples after purification over Sephadex G10.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histochemical detection of apoptosis in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of ICE slows ALS in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia-specific localisation of a novel calcium binding protein, Iba1

1 reference

https://pubmed.ncbi.nlm.nih.gov/14985426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3309-03.2004

1 reference

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24 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14985426%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14985426%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

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