A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of stat transcription factors. (Q44792911)

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25 December 2019

title

A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of stat transcription factors (English)

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25 December 2019

4

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25 December 2019

Uwe Vinkemeier

5

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25 December 2019

author name string

Thomas Meyer

1

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25 December 2019

Lisa Hendry

2

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25 December 2019

Andreas Begitt

3

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25 December 2019

language of work or name

English

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publication date

9 March 2004

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Journal of Biological Chemistry

25 December 2019

published in

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25 December 2019

volume

279

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25 December 2019

issue

18

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25 December 2019

page(s)

18998-19007

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Phosphotyrosine signaling and the single cell:metazoan boundary

25 December 2019

cites work

1 reference

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Jaks and Stats in signaling by the cytokine receptor superfamily

21 January 2018

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A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

21 January 2018

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Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

21 January 2018

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Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process

21 January 2018

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DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1.

21 January 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

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Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

21 January 2018

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

21 January 2018

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

21 January 2018

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

21 January 2018

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Cooperative binding of Stat1-2 heterodimers and ISGF3 to tandem DNA elements

21 January 2018

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The significance of tetramerization in promoter recruitment by Stat5.

21 January 2018

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Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain

21 January 2018

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Functional importance of Stat3 tetramerization in activation of the alpha 2-macroglobulin gene

21 January 2018

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Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1.

21 January 2018

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Amino-terminal signal transducer and activator of transcription (STAT) domains regulate nuclear translocation and STAT deactivation.

21 January 2018

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Structure of the amino-terminal protein interaction domain of STAT-4

21 January 2018

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A reinterpretation of the dimerization interface of the N-terminal domains of STATs

21 January 2018

1 reference

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Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain

21 January 2018

1 reference

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Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways

21 January 2018

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DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites

21 January 2018

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Interaction of STAT5 dimers on two low affinity binding sites mediates interleukin 2 (IL-2) stimulation of IL-2 receptor alpha gene transcription

21 January 2018

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A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5

21 January 2018

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

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Identification of a nuclear Stat1 protein tyrosine phosphatase

21 January 2018

1 reference

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Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1.

21 January 2018

1 reference

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Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3

21 January 2018

1 reference

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Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.

21 January 2018

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Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation.

21 January 2018

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The proteasome regulates receptor-mediated endocytosis of interleukin-2.

21 January 2018

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A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus

21 January 2018

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Identification of Shp-2 as a Stat5A phosphatase

21 January 2018

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Prolactin induces SHP-2 association with Stat5, nuclear translocation, and binding to the beta-casein gene promoter in mammary cells

21 January 2018

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Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor

21 January 2018

1 reference

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A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter

21 January 2018

1 reference

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Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

21 January 2018

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N-domain-dependent nonphosphorylated STAT4 dimers required for cytokine-driven activation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M400766200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15010467%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference