Rhodopsin activation exposes a key hydrophobic binding site for the transducin alpha-subunit C terminus (Q44834954)

6 December 2017

Rhodopsin activation exposes a key hydrophobic binding site for the transducin alpha-subunit C terminus (English)

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6 December 2017

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Jay M Janz

1

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PubMed ID

15070895

6 December 2017

David L Farrens

series ordinal

2

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PubMed ID

15070895

6 December 2017

language of work or name

English

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publication date

7 April 2004

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Journal of Biological Chemistry

6 December 2017

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6 December 2017

279

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6 December 2017

29767-29773

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6 December 2017

28

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Activation of rhodopsin: new insights from structural and biochemical studies

6 December 2017

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G protein-coupled receptor rhodopsin: a prospectus

21 January 2018

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Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking

21 January 2018

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Phototransduction: crystal clear

21 January 2018

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Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study

21 January 2018

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NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR.

21 January 2018

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Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

21 January 2018

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Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch

21 January 2018

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Molecular mechanisms involved in muscarinic acetylcholine receptor-mediated G protein activation studied by insertion mutagenesis

21 January 2018

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Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor

21 January 2018

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Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

21 January 2018

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Molecular basis of receptor/G protein coupling selectivity studied by coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits

21 January 2018

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G protein-coupled receptors. II. Mechanism of agonist activation.

21 January 2018

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Structure. Rhodopsin sees the light

21 January 2018

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A conformational trigger for activation of a G protein by a G protein-coupled receptor

21 January 2018

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Potent peptide analogues of a G protein receptor-binding region obtained with a combinatorial library

21 January 2018

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Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin.

21 January 2018

1 reference

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Light-activated rhodopsin induces structural binding motif in G protein alpha subunit

21 January 2018

1 reference

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Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings

21 January 2018

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Three cytoplasmic loops of rhodopsin interact with transducin

21 January 2018

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Functional interaction between bovine rhodopsin and G protein transducin

21 January 2018

1 reference

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Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent

21 January 2018

1 reference

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Stability of dark state rhodopsin is mediated by a conserved ion pair in intradiscal loop E-2.

21 January 2018

1 reference

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Structure and function in rhodopsin: covalent crosslinking of the rhodopsin (metarhodopsin II)-transducin complex--the rhodopsin cytoplasmic face links to the transducin alpha subunit

21 January 2018

1 reference

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Structure and function in rhodopsin: kinetic studies of retinal binding to purified opsin mutants in defined phospholipid-detergent mixtures serve as probes of the retinal binding pocket

21 January 2018

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Engineering a functional blue-wavelength-shifted rhodopsin mutant

21 January 2018

1 reference

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The molar extinction of rhodopsin

21 January 2018

1 reference

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Signaling states of rhodopsin. Formation of the storage form, metarhodopsin III, from active metarhodopsin II

21 January 2018

1 reference

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Deactivation of rhodopsin in the transition from the signaling state meta II to meta III involves a thermal isomerization of the retinal chromophore C[double bond]D.

21 January 2018

1 reference

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Mapping proximity within proteins using fluorescence spectroscopy. A study of T4 lysozyme showing that tryptophan residues quench bimane fluorescence

21 January 2018

1 reference

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Light-induced exposure of the cytoplasmic end of transmembrane helix seven in rhodopsin

21 January 2018

1 reference

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Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

21 January 2018

1 reference

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Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducin alpha and gamma subunits.

21 January 2018

1 reference

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Advances in Determination of a High-Resolution Three-Dimensional Structure of Rhodopsin, a Model of G-Protein-Coupled Receptors (GPCRs)

21 January 2018

1 reference

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Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

1 reference

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Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography.

21 January 2018

1 reference

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Rhodopsin determinants for transducin activation: a gain-of-function approach

21 January 2018

1 reference

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Light-induced changes in the structure and accessibility of the cytoplasmic loops of rhodopsin in the activated MII state

21 January 2018

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A hot spot of binding energy in a hormone-receptor interface

21 January 2018

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Elucidation of the Nature of the Conformational Changes of the EF-interhelical Loop in Bacteriorhodopsin and of the Helix VIII on the Cytoplasmic Surface of Bovine Rhodopsin: A Time-resolved Fluorescence Depolarization Study

21 January 2018

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Evidence that helix 8 of rhodopsin acts as a membrane-dependent conformational switch

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M402567200

1 reference

6 December 2017

1 reference

PubMed ID

15070895