DNA vaccines expressing soluble CD4-envelope proteins fused to C3d elicit cross-reactive neutralizing antibodies to HIV-1. (Q44862450)

6 December 2017

DNA vaccines expressing soluble CD4-envelope proteins fused to C3d elicit cross-reactive neutralizing antibodies to HIV-1. (English)

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6 December 2017

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Joseph F Bower

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6 December 2017

Thomas D Green

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2

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6 December 2017

Ted M Ross

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3

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6 December 2017

language of work or name

English

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publication date

1 October 2004

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6 December 2017

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6 December 2017

328

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2

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292-300

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Elicitation of neutralizing antibodies with DNA vaccines expressing soluble stabilized human immunodeficiency virus type 1 envelope glycoprotein trimers conjugated to C3d.

6 December 2017

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The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

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C3d of complement as a molecular adjuvant: bridging innate and acquired immunity

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Covalently crosslinked complexes of human immunodeficiency virus type 1 (HIV-1) gp120 and CD4 receptor elicit a neutralizing immune response that includes antibodies selective for primary virus isolates

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Expression and characterization of a single-chain polypeptide analogue of the human immunodeficiency virus type 1 gp120-CD4 receptor complex

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Crosslinked HIV-1 envelope-CD4 receptor complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaques

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Clinical trials of HIV vaccines.

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C3d enhancement of neutralizing antibodies to measles hemagglutinin

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Enhancement of antibodies to the human immunodeficiency virus type 1 envelope by using the molecular adjuvant C3d.

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Cutting edge: C3d functions as a molecular adjuvant in the absence of CD21/35 expression

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Analysis of the immunogenic properties of a single-chain polypeptide analogue of the HIV-1 gp120?CD4 complex in transgenic mice that produce human immunoglobulins

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T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

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Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines

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Strategies for an HIV vaccine

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Use of DNAs expressing HIV-1 Env and noninfectious HIV-1 particles to raise antibody responses in mice.

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The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family.

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Defining the Protective Antibody Response for HIV-1

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Induction of heterosubtypic immunity to influenza A virus using a DNA vaccine expressing hemagglutinin-C3d fusion proteins

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Gene gun-based nucleic acid immunization: elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA

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CD4 binding site antibodies inhibit human immunodeficiency virus gp120 envelope glycoprotein interaction with CCR5

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DNA vaccines for viral infections: basic studies and applications

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C3d enhancement of antibodies to hemagglutinin accelerates protection against influenza virus challenge

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Enhanced avidity maturation of antibody to human immunodeficiency virus envelope: DNA vaccination with gp120-C3d fusion proteins

7 January 2021

1 reference

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Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120.

7 January 2021

1 reference

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Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding

7 January 2021

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HIV vaccine development: lessons from the past and promise for the future

7 January 2021

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Mouse strain-dependent differences in enhancement of immune responses by C3d.

7 January 2021

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CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

7 January 2021

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Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

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CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

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The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

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Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein

7 January 2021

1 reference

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Evolution of envelope-specific antibody responses in monkeys experimentally infected or immunized with simian immunodeficiency virus and its association with the development of protective immunity

7 January 2021

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7 January 2021

Simian immunodeficiency virus DNA vaccine trial in macaques.

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7 January 2021

Evaluation of antiviral drugs and neutralizing antibodies to human immunodeficiency virus by a rapid and sensitive microtiter infection assay.

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7 January 2021

Role of chemokine receptors in HIV-1 infection and pathogenesis

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7 January 2021

Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding

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7 January 2021

CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization

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7 January 2021

Lack of correlation between soluble CD4-induced shedding of the human immunodeficiency virus type 1 exterior envelope glycoprotein and subsequent membrane fusion events

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.07.031

7 January 2021

10.1016/J.VIROL.2004.07.031

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DOI

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6 December 2017

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