The serotonin 5-HT2A receptors antagonist M100907 prevents impairment in attentional performance by NMDA receptor blockade in the rat prefrontal cortex (Q44883674)

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English	The serotonin 5-HT2A receptors antagonist M100907 prevents impairment in attentional performance by NMDA receptor blockade in the rat prefrontal cortex	scientific article

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scholarly article

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Europe PubMed Central

7 December 2017

The serotonin 5-HT2A receptors antagonist M100907 prevents impairment in attentional performance by NMDA receptor blockade in the rat prefrontal cortex (English)

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Europe PubMed Central

7 December 2017

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Carli Mirjana

1

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Europe PubMed Central

7 December 2017

Marta Baviera

2

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Europe PubMed Central

7 December 2017

Roberto W Invernizzi

3

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Europe PubMed Central

7 December 2017

Claudia Balducci

4

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Europe PubMed Central

7 December 2017

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1 September 2004

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Europe PubMed Central

7 December 2017

Neuropsychopharmacology

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Europe PubMed Central

7 December 2017

29

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Europe PubMed Central

7 December 2017

9

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Europe PubMed Central

7 December 2017

1637-1647

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Europe PubMed Central

7 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.npp.1300479

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Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells.

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Catecholamine regulation of the prefrontal cortex

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Blockade of NMDA receptors located at the dorsomedial prefrontal cortex impairs spatial working memory in rats.

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A review of central 5-HT receptors and their function

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SR46349-B, a 5-HT(2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens

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Information processing and attention dysfunctions in schizophrenia

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Effects of lesions to ascending noradrenergic neurones on performance of a 5-choice serial reaction task in rats; implications for theories of dorsal noradrenergic bundle function based on selective attention and arousal.

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Serotonin2 receptor agonists and serotonergic anorectic drugs affect rats' performance differently in a five-choice serial reaction time task

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Deficits in impulse control associated with tonically-elevated serotonergic function in rat prefrontal cortex

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Schizophrenia, training paradigms, and the Wisconsin Card Sorting Test redux

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M100907, a selective 5-HT(2A) receptor antagonist, attenuates phencyclidine-induced Fos expression in discrete regions of rat brain

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Central 5-HT depletion enhances impulsive responding without affecting the accuracy of attentional performance: interactions with dopaminergic mechanisms.

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Doubly dissociable effects of median- and dorsal-raphé lesions on the performance of the five-choice serial reaction time test of attention in rats.

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Evaluation of the NR2B-selective NMDA receptor antagonist Ro 63-1908 on rodent behaviour: evidence for an involvement of NR2B NMDA receptors in response inhibition

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The 5-HT2A receptor antagonist M100,907 attenuates motor and 'impulsive-type' behaviours produced by NMDA receptor antagonism

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Differences in frontal cortical activation by a working memory task after substitution of risperidone for typical antipsychotic drugs in patients with schizophrenia

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5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

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Recent advances in the phencyclidine model of schizophrenia

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The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia

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Prefrontal cortical involvement in phencyclidine-induced activation of the mesolimbic dopamine system: behavioral and neurochemical evidence

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Coordination of actions and habits in the medial prefrontal cortex of rats.

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Activation of 5-HT2A receptors impairs response control of rats in a five-choice serial reaction time task.

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Studies on the involvement of the dopaminergic system in the 5-HT2 agonist (DOI)-induced premature responding in a five-choice serial reaction time task

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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

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Phencyclidine exacerbates attentional deficits in a neurodevelopmental rat model of schizophrenia

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5-HT(2A) receptor antagonism potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and inhibits that in the nucleus accumbens in a dose-dependent manner

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Systemic PCP treatment elevates brain extracellular 5-HT: a microdialysis study in awake rats.

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MK-801-induced hyperlocomotion: differential effects of M100907, SDZ PSD 958 and raclopride

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The Mechanism of Action of Novel Antipsychotic Drugs

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The role of serotonin in antipsychotic drug action

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Serotonin receptors: their key role in drugs to treat schizophrenia

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The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia

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Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

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The cerebral cortex of the rat and visual attentional function: dissociable effects of mediofrontal, cingulate, anterior dorsolateral, and parietal cortex lesions on a five-choice serial reaction time task.

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Unique behavioral effects of the NMDA antagonist, CPP, upon injection into the medial pre-frontal cortex of rats.

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Contrasting mechanisms of impaired attentional set-shifting in patients with frontal lobe damage or Parkinson's disease.

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The frontal cortex of the rat and visual attentional performance: dissociable functions of distinct medial prefrontal subregions

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Double dissociation of serotonergic and dopaminergic mechanisms on attentional performance using a rodent five-choice reaction time task

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Changes in activities of dopamine and serotonin systems in the frontal cortex underlie poor choice accuracy and impulsivity of rats in an attention task.

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The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry

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Glutamatergic and dopaminergic afferents to the prefrontal cortex regulate spatial working memory in rats.

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Differential effects of three 5-HT receptor antagonists on the performance of rats in attentional and working memory tasks.

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The hallucinogen 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI) increases cortical extracellular glutamate levels in rats

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Specific impairments of planning

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Glutamatergic mechanisms in schizophrenia

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M100907, a serotonin 5-HT2A receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and Wistar rats

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Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats.

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Exploring the Central Executive

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10.1038/SJ.NPP.1300479

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Europe PubMed Central

7 December 2017

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Europe PubMed Central

7 December 2017

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