Intracellular signaling pathways involved in Gas6-Axl-mediated survival of endothelial cells (Q44886463)

7 December 2017

Intracellular signaling pathways involved in Gas6-Axl-mediated survival of endothelial cells (English)

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7 December 2017

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Ines Hasanbasic

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7 December 2017

Jessica Cuerquis

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2

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7 December 2017

Brian Varnum

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3

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7 December 2017

Mark D Blostein

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7 December 2017

6 May 2004

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American Journal of Physiology Heart and Circulatory Physiology

7 December 2017

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7 December 2017

287

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7 December 2017

3

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7 December 2017

H1207-13

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Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.

7 December 2017

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Biochemical pathways of caspase activation during apoptosis

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Regulation of endothelial cell survival and apoptosis during angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Acidosis inhibits endothelial cell apoptosis and function and induces basic fibroblast growth factor and vascular endothelial growth factor expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Hypoxia and HIF-1alpha stability: another stress-sensing mechanism for Shc.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Cellular survival: a play in three Akts

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

The transcription factor NF-kappa B and the regulation of vascular cell function

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Gas6 anti-apoptotic signaling requires NF-kappa B activation.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Progression of atheroma: a struggle between death and procreation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Reevaluation of the roles of protein S and Gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Requirement of phosphatidylinositol 3-kinase-dependent pathway and Src for Gas6-Axl mitogenic and survival activities in NIH 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Gas6-mediated survival in NIH3T3 cells activates stress signalling cascade and is independent of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Gas6 binding to photoreceptor outer segments requires gamma-carboxyglutamic acid (Gla) and Ca(2+) and is required for OS phagocytosis by RPE cells in vitro

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Outer segment phagocytosis by cultured retinal pigment epithelial cells requires Gas6.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Gas 6 promotes Axl-mediated survival in pulmonary endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Multiple signals converging on NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Phosphatidylinositol 3-OH kinase-Akt/protein kinase B pathway mediates Gas6 induction of scavenger receptor a in immortalized human vascular smooth muscle cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Growth arrest-specific gene 6 is involved in glomerular hypertrophy in the early stage of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Tyro 3 receptor tyrosine kinase and its ligand, Gas6, stimulate the function of osteoclasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Expression of receptor tyrosine kinase Axl and its ligand Gas6 in rheumatoid arthritis: evidence for a novel endothelial cell survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Gas6 rescues cortical neurons from amyloid beta protein-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Gas6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Gas6 induces mesangial cell proliferation via latent transcription factor STAT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Essential role of Gas6 for glomerular injury in nephrotoxic nephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

Vascular Smooth Muscle Cell-derived, Gla-containing Growth-potentiating Factor for Ca-mobilizing Growth Factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00020.2004

10.1152/AJPHEART.00020.2004

21 January 2018

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7 December 2017

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