Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1alpha. (Q44927471)

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29 December 2019

title

Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1alpha (English)

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2

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Michihiro Tateyama

1

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29 December 2019

author name string

Hiroyasu Nakata

3

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Osamu Saito

4

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Yoshihiro Kubo

5

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publication date

6 June 2004

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Nature Structural & Molecular Biology

29 December 2019

published in

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volume

11

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issue

7

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page(s)

637-642

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Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice.

29 December 2019

cites work

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Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

31 March 2020

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Antibodies inactivating mGluR1 metabotropic glutamate receptor block long-term depression in cultured Purkinje cells

31 March 2020

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Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

31 March 2020

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Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor

31 March 2020

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Measurement of the millisecond activation switch of G protein-coupled receptors in living cells

31 March 2020

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Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

31 March 2020

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Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.

31 March 2020

1 reference

Erythropoietin receptor activation by a ligand-induced conformation change

31 March 2020

1 reference

Amino acid mutagenesis of the ligand binding site and the dimer interface of the metabotropic glutamate receptor 1. Identification of crucial residues for setting the activated state

31 March 2020

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Functional identification of Gd3+ binding site of metabotropic glutamate receptor 1alpha

31 March 2020

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Role of the second and third intracellular loops of metabotropic glutamate receptors in mediating dual signal transduction activation

31 March 2020

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The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins.

31 March 2020

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Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin

31 March 2020

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ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer

31 March 2020

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Conformational Rearrangements Associated with the Gating of the G Protein-Coupled Potassium Channel Revealed by FRET Microscopy

31 March 2020

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Gi protein activation in intact cells involves subunit rearrangement rather than dissociation

31 March 2020

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Visualization of the spatial and temporal dynamics of intracellular signaling

31 March 2020

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A real-time view of life within 100 nm of the plasma membrane

31 March 2020

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Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopes

31 March 2020

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Probing intermolecular protein-protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET).

31 March 2020

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The molecular structure of green fluorescent protein

31 March 2020

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A cluster of basic residues in the carboxyl-terminal tail of the short metabotropic glutamate receptor 1 variants impairs their coupling to phospholipase C.

31 March 2020

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Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives.

31 March 2020

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The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate recepto

31 March 2020

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Structural basis for a Ca2+-sensing function of the metabotropic glutamate receptors

31 March 2020

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A modulatory effect of extracellular Ca2+ on type 1alpha metabotropic glutamate receptor-mediated signalling.

31 March 2020

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Crystal structure of rhodopsin: A G protein-coupled receptor

31 March 2020

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Membrane topology of a metabotropic glutamate receptor

31 March 2020

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Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors

31 March 2020

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Effects of coexpression with Homer isoforms on the function of metabotropic glutamate receptor 1alpha

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB770

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