Transplacental carcinogenicity of 3'-azido-3'-deoxythymidine in B6C3F1 mice and F344 rats (Q44927777)

7 December 2017

title

Transplacental carcinogenicity of 3'-azido-3'-deoxythymidine in B6C3F1 mice and F344 rats (English)

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7 December 2017

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3

Steven K Seilkop

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7 December 2017

11

Vernon E Walker

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7 December 2017

1

Dale M Walker

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7 December 2017

9

Fletcher F Hahn

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7 December 2017

David E Malarkey

2

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7 December 2017

Frederick A Ruecker

4

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7 December 2017

Kathleen A Funk

5

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7 December 2017

Marilyn J Wolfe

6

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7 December 2017

Christopher P Treanor

7

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7 December 2017

Julie F Foley

8

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7 December 2017

Jerry F Hardisty

10

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7 December 2017

publication date

1 April 2007

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Environmental and Molecular Mutagenesis

7 December 2017

published in

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7 December 2017

volume

48

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7 December 2017

issue

3-4

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7 December 2017

page(s)

283-298

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Transplacental genotoxicity of combined antiretroviral nucleoside analogue therapy in Erythrocebus patas monkeys

7 December 2017

cites work

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Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT

21 January 2018

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Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine

21 January 2018

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Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats

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7 January 2021

A transplacental carcinogenicity bioassay in CD-1 mice with zidovudine.

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7 January 2021

Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples

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7 January 2021

Ratio estimates, the delta method, and quantal response tests for increased carcinogenicity

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7 January 2021

Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine and dideoxyinosine via maternal dosing, nursing, and direct gavage

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7 January 2021

Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group

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7 January 2021

Lack of long-term effects of in utero exposure to zidovudine among uninfected children born to HIV-infected women. Pediatric AIDS Clinical Trials Group Protocol 219/076 Teams.

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7 January 2021

Induction of micronuclei by low doses of azidothymidine (AZT)

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7 January 2021

Hemangiomas and other congenital malformations in infants exposed to antiretroviral therapy in utero

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7 January 2021

Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice

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7 January 2021

Irreversible telomere shortening by 3'-azido-2',3'-dideoxythymidine (AZT) treatment

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7 January 2021

Genotoxic activity of azidothymidine (AZT) in in vitro systems

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7 January 2021

Spontaneous neoplasm incidences in Fischer 344 rats and B6C3F1 mice in two-year carcinogenicity studies: a National Toxicology Program update

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7 January 2021

Protein A, avidin, and biotin in immunohistochemistry

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7 January 2021

Antiretroviral therapies in pregnancy: maternal, fetal and neonatal effects. Swiss HIV Cohort Study, the Swiss Collaborative HIV and Pregnancy Study, and the Swiss Neonatal HIV Study

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7 January 2021

Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

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7 January 2021

Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells

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7 January 2021

Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs

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7 January 2021

Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring

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7 January 2021

The hepatic endothelial carcinogen riddelliine induces endothelial apoptosis, mitosis, S phase, and p53 and hepatocytic vascular endothelial growth factor expression after short-term exposure.

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7 January 2021

Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.

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7 January 2021

Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero

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7 January 2021

p53 Gene deletions in paraffin-preserved lymphoid tumors from irradiated mice

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7 January 2021

Induction of micronuclei in mouse bone marrow cells: an evaluation of nucleoside analogues used in the treatment of AIDS.

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7 January 2021

Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs

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7 January 2021

Using 3'-azido-2',3'-dideoxythymidine (AZT) to prevent perinatal human immunodeficiency virus transmission and risk of transplacental carcinogenesis

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7 January 2021

Tumors of the nervous system in carcinogenic hazard identification

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7 January 2021

The effect of body weight on tumor incidence and carcinogenicity testing in B6C3F1 mice and F344 rats

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7 January 2021

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7 January 2021

Efficiency and side effects of antiretroviral treatment of HIV infected pregnant women

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7 January 2021

Maternal viral load, zidovudine treatment, and the risk of transmission of human immunodeficiency virus type 1 from mother to infant. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group

1 reference

7 January 2021

Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations

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7 January 2021

Antiretroviral therapy during pregnancy and the risk of an adverse outcome

1 reference

7 January 2021

Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in B6C3F(1)/Tk+/- mice treated neonatally with zidovudine and lamivudine

1 reference

7 January 2021

3'-azido-3'-deoxythymidine induces deletions in L5178Y mouse lymphoma cells

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7 January 2021

Identifiers

DOI

10.1002/EM.20297

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7 December 2017

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