Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein (Q44946713)

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English	Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

(S)-(−)-colchicine

1 reference

based on heuristic

inferred from title

author name string

Arik Dahan

1

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Gordon L Amidon

2

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

publication date

2 December 2008

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Pharmaceutical Research

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Europe PubMed Central

PubMed publication ID

7 December 2017

26

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

883-892

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Oral absorption characteristics and pharmacokinetics of colchicine in healthy volunteers after single and multiple doses

1 reference

https://api.crossref.org/works/10.1007%2FS11095-008-9789-7

21 January 2018

Relationship between time of intake of grapefruit juice and its effect on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects

1 reference

https://api.crossref.org/works/10.1007%2FS11095-008-9789-7

21 January 2018

Grapefruit-drug interactions: can interactions with drugs be avoided?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colchicine and HMG Co-A reductase inhibitors induced myopathy-a case report

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Model-independent pharmacokinetics of colchicine after oral administration to healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and absolute bioavailability of colchicine after i.v. and oral administration in healthy human volunteers and elderly subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute pancreatitis related to therapeutic dosing with colchicine: a case report

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal first pass metabolism of midazolam in liver cirrhosis --effect of grapefruit juice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of liver dysfunction on colchicine pharmacokinetics in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of citrus juices with felodipine and nifedipine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-Glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: the influence of culturing conditions and drug exposure on P-gp expression levels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute colchicine intoxication--possible role of erythromycin administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal data: the contributions of the Ussing Chamber and perfusion systems to predicting human oral drug delivery in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Segmental-dependent membrane permeability along the intestine following oral drug administration: Evaluation of a triple single-pass intestinal perfusion (TSPIP) approach in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improvement of the bioavailability of colchicine in rats by co-administration of D-alpha-tocopherol polyethylene glycol 1000 succinate and a polyethoxylated derivative of 12-hydroxy-stearic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term evaluation of colchicine in the treatment of scleroderma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation of flavonoids and furanocoumarins in grapefruit juices: a potential source of variability in grapefruit juice-drug interaction studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The suitability of an in situ perfusion model for permeability determinations: utility for BCS class I biowaiver requests

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-grapefruit juice interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary biliary cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Profile of P-glycoprotein distribution in the rat and its possible influence on the salbutamol intestinal absorption process.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of citrus soft drinks relative to grapefruit juice on ciclosporin disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular properties of WHO essential drugs and provisional biopharmaceutical classification

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical practice. Gout

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accidental colchicine overdose. A case report and literature review

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Food-drug interaction: grapefruit juice augments drug bioavailability--mechanism, extent and relevance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic approaches to familial Mediterranean fever. What do we know and where are we going to?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colchicine biotransformation by human liver microsomes. Identification of CYP3A4 as the major isoform responsible for colchicine demethylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol enhances the hemodynamic effects of felodipine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colchicine: 1998 update.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatal interaction between clarithromycin and colchicine in patients with renal insufficiency: a retrospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavanone absorption after naringin, hesperidin, and citrus administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Near fatal acute colchicine intoxication in a child. A case report

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colchicine therapy for familial mediterranean fever. A double-blind trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison between permeability coefficients in rat and human jejunum

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grapefruit juice-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetraparesis associated with colchicine is probably due to inhibition by verapamil of the P-glycoprotein efflux pump in the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastrointestinal, hepatorenal, and neuromuscular toxicity caused by cyclosporine-colchicine interaction in renal transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of grapefruit juice on cyclosporin A pharmacokinetics in pediatric renal transplant patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grapefruit Juice–Drug Interactions: Grapefruit Juice and Its Components Inhibit P‐Glycoprotein (ABCB1) Mediated Transport of Talinolol in Caco‐2 Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between time after intake of grapefruit juice and the effect on pharmacokinetics and pharmacodynamics of nisoldipine in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048359

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-008-9789-7

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

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