Leishmania major LmACR2 is a pentavalent antimony reductase that confers sensitivity to the drug pentostam. (Q44954103)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

title

Leishmania major LmACR2 is a pentavalent antimony reductase that confers sensitivity to the drug pentostam (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

1 reference

6 February 2019

As/Sb Reductase, putative

0 references

As/Sb Reductase, putative

0 references

As/Sb Reductase, putative

0 references

1 reference

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Barry P. Rosen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

author name string

Yao Zhou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Nadine Messier

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Rita Mukhopadhyay

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

language of work or name

English

0 references

publication date

25 June 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

30 August 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

issue

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

page(s)

37445-37451

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic

30 August 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Arsenic trioxide uptake by human and rat aquaglyceroporins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

As(III) and Sb(III) uptake by GlpF and efflux by ArsB in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Pathways of As(III) detoxification in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Arsenate reductases in prokaryotes and eukaryotes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Reduction of anti-leishmanial pentavalent antimonial drugs by a parasite-specific thiol-dependent reductase, TDR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Saccharomyces cerevisiae ACR2 gene encodes an arsenate reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

The phosphatase C(X)5R motif is required for catalytic activity of the Saccharomyces cerevisiae Acr2p arsenate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Purification and characterization of ACR2p, the Saccharomyces cerevisiae arsenate reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Directed evolution of a yeast arsenate reductase into a protein-tyrosine phosphatase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Structure and function of the protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

A model of Cdc25 phosphatase catalytic domain and Cdk-interaction surface based on the presence of a rhodanese homology domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Arsenate reduction mediated by the plasmid-encoded ArsC protein is coupled to glutathione.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Reactivity of glutaredoxins 1, 2, and 3 from Escherichia coli shows that glutaredoxin 2 is the primary hydrogen donor to ArsC-catalyzed arsenate reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Calculation of protein extinction coefficients from amino acid sequence data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Monitoring of total antimony and its species by ICP-MS and on-line ion chromatography in biological samples from patients treated for leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Properties of the arsenate reductase of plasmid R773.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Metabolism and functions of trypanothione in the Kinetoplastida

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

Catalytic properties, thiol pK value, and redox potential of Trypanosoma brucei tryparedoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404383200

21 January 2018

Identifiers

DOI

10.1074/JBC.M404383200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15220340%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

1 reference