Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic T lymphocytes carrying strong ability to suppress HIV-1 replication. (Q44965239)

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scientific article published on 3 December 2010

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English	Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic T lymphocytes carrying strong ability to suppress HIV-1 replication.	scientific article published on 3 December 2010

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18 January 2020

Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic T lymphocytes carrying strong ability to suppress HIV-1 replication (English)

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18 January 2020

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Masao Hashimoto

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18 January 2020

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Kazutaka Honda

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18 January 2020

Nan Zheng

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18 January 2020

Hayato Murakoshi

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18 January 2020

Keiko Sakai

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18 January 2020

Mohamed Ali Borghan

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18 January 2020

Takayuki Chikata

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18 January 2020

Madoka Koyanagi

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18 January 2020

Yoshiko Tamura

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18 January 2020

Hiroyuki Gatanaga

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18 January 2020

Shinichi Oka

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18 January 2020

Masafumi Takiguchi

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18 January 2020

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3 December 2010

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18 January 2020

European Journal of Immunology

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18 January 2020

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18 January 2020

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18 January 2020

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18 January 2020

Impact of MHC class I diversity on immune control of immunodeficiency virus replication

1 reference

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Long-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101

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Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

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Immunologic control of HIV-1.

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Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

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Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.

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Different abilities of escape mutant-specific cytotoxic T cells to suppress replication of escape mutant and wild-type human immunodeficiency virus type 1 in new hosts

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The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells

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Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I trafficking

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HIV Nef: role in pathogenesis and viral fitness

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The physiological relevance of CD4 receptor down-modulation during HIV infection

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HLA-dependent variations in human immunodeficiency virus Nef protein alter peptide/HLA binding

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Selection of escape mutation by Pol154-162-specific cytotoxic T cells among chronically HIV-1-infected HLA-B*5401-positive individuals

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Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.

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Cellular immune responses to HIV.

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Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child

1 reference

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Adaptation of HIV-1 to human leukocyte antigen class I

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Low HLA-C expression at cell surfaces correlates with increased turnover of heavy chain mRNA.

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Nef interference with HIV-1-specific CTL antiviral activity is epitope specific

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A whole-genome association study of major determinants for host control of HIV-1

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Characterization of an HLA-C-restricted CTL response in chronic HIV infection.

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HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load

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Central role of reverting mutations in HLA associations with human immunodeficiency virus set point

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Mapping cross-clade HIV-1 vaccine epitopes using a bioinformatics approach

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Different effects of Nef-mediated HLA class I down-regulation on human immunodeficiency virus type 1-specific CD8(+) T-cell cytolytic activity and cytokine production

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Different in vivo effects of HIV-1 immunodominant epitope-specific cytotoxic T lymphocytes on selection of escape mutant viruses.

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Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

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Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulation

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HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.

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Identification and characterization of HLA-B*5401-restricted HIV-1-Nef and Pol-specific CTL epitopes.

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Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress human immunodeficiency virus type 1 (HIV-1) replication in HIV-1-infected CD4+ T cells and macrophages

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Mutations other than 103N in human immunodeficiency virus type 1 reverse transcriptase (RT) emerge from K103R polymorphism under non-nucleoside RT inhibitor pressure

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Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

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Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

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Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

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Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

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Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection

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Cutting Edge: Epitope-dependent effect of Nef-mediated HLA class I down-regulation on ability of HIV-1-specific CTLs to suppress HIV-1 replication

1 reference

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7 January 2021

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