Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease. (Q45007596)

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English	Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease.	scientific article

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31 December 2019

Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease (English)

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31 December 2019

Parkinson's disease

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Jean-Christophe Corvol

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31 December 2019

Jean-Antoine Girault

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Emmanuel Valjent

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Etienne C. Hirsch

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31 December 2019

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Denis Hervé

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Marie-Paule Muriel

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Jean Féger

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Naïma Hanoun

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1 August 2004

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31 December 2019

Journal of Neuroscience

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7007-7014

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31 December 2019

Levodopa induces a cytoplasmic localization of D1 dopamine receptors in striatal neurons in Parkinson's disease.

1 reference

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12 December 2020

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Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Dopamine-mediated gene regulation in models of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

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Addiction, dopamine, and the molecular mechanisms of memory

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12 December 2020

based on heuristic

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A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G(olf)alpha mediates dopamine D1 receptor signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levodopa motor complications in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular effects of dopamine on striatal-projection pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

deltaFosB: a molecular switch underlying long-term neural plasticity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galpha(olf) is necessary for coupling D1 and A2a receptors to adenylyl cyclase in the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine D(1) receptor expression in human basal ganglia and changes in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

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The olfactory G protein G(alphaolf) possesses a lower GDP-affinity and deactivates more rapidly than G(salphashort): consequences for receptor-coupling and adenylyl cyclase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of levodopa-induced dyskinesia: potential for new therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Differential dependence of the D1 and D5 dopamine receptors on the G protein gamma 7 subunit for activation of adenylylcyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

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The neurobiology of slow synaptic transmission

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated levels of DeltaFosB and RGS9 in striatum in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased dopamine receptor signaling and dopamine receptor-G protein coupling in denervated striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

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Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

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mRNA and protein expression of selective alpha subunits of G proteins are abnormal in prefrontal cortex of suicide victims.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Loss of G protein gamma 7 alters behavior and reduces striatal alpha(olf) level and cAMP production

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

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Sensitization of dopamine-stimulated adenylyl cyclase in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated rhesus monkeys and patients with idiopathic Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Brain dopamine-stimulated adenylyl cyclase activity in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G(olf) in the basal ganglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, Golf

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Striatal phosphoproteins in Parkinson disease and progressive supranuclear palsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis for two forms of the G protein that stimulates adenylate cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective D1 and D2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of protein using bicinchoninic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain glutamate decarboxylase in Parkinson's disease with particular reference to a premortem severity index.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor basis for dopaminergic supersensitivity in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations of GABAergic neurons in the basal ganglia of patients with progressive supranuclear palsy: an in situ hybridization study of GAD67 messenger RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmembrane signalling systems in the brain of patients with Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of basal adenylate cyclase activity in neuroblastoma x glioma hybrid, NG108-15, cells transfected to express the human beta 2 adrenoceptor: evidence for empty receptor stimulation of the adenylate cyclase cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal G-proteins: effects of unilateral 6-hydroxydopamine lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist regulation of cellular G protein levels and distribution: mechanisms and functional implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G(olf) and Gs in rat basal ganglia: possible involvement of G(olf) in the coupling of dopamine D1 receptor with adenylyl cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine D1 receptors in Parkinson's disease and striatonigral degeneration: a positron emission tomography study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic alterations in dopaminergic neurotransmission produce a persistent elevation of deltaFosB-like protein(s) in both the rodent and primate striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bilateral 6-hydroxydopamine-induced lesion of the nigrostriatal dopamine pathway reproduces the effects of unilateral lesion on substance P but not on enkephalin expression in rat basal ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of dopamine D3 receptor expression as a mechanism of behavioral sensitization to levodopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo studies on striatal dopamine D1 and D2 site binding in L-dopa-treated Parkinson's disease patients with and without dyskinesias.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in G(olf) are anosmic

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A complex program of striatal gene expression induced by dopaminergic stimulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of dynorphin and enkephalin in the regulation of striatal output pathways and behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/15295036

12 December 2020

based on heuristic

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Identifiers

10.1523/JNEUROSCI.0676-04.2004

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31 December 2019

1 reference

Europe PubMed Central

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31 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15295036%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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