Increased site 1 affinity improves biopotency of porcine growth hormone. Evidence against diffusion dependent receptor dimerization (Q45009213)

8 December 2017

Increased site 1 affinity improves biopotency of porcine growth hormone. Evidence against diffusion dependent receptor dimerization (English)

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8 December 2017

4

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8 December 2017

Yu Wan

1

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8 December 2017

Andrew McDevitt

series ordinal

2

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8 December 2017

Bojiang Shen

series ordinal

3

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8 December 2017

Michael J Waters

series ordinal

5

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8 December 2017

language of work or name

English

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publication date

5 August 2004

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Journal of Biological Chemistry

8 December 2017

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8 December 2017

279

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8 December 2017

43

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8 December 2017

44775-44784

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Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity

8 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

A sequential dimerization mechanism for erythropoietin receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Preparation of a recombinant chimaera of insulin-like growth factor II and interleukin 3 with high proliferative potency for haemopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Epitope map for a growth hormone receptor agonist monoclonal antibody, MAb 263.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Evidence from the use of monoclonal antibody probes for structural heterogeneity of the growth hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Aspartate 171 is the major primate-specific determinant of human growth hormone. Engineering porcine growth hormone to activate the human receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Structure of a phage display-derived variant of human growth hormone complexed to two copies of the extracellular domain of its receptor: evidence for strong structural coupling between receptor binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Efficiency of signalling through cytokine receptors depends critically on receptor orientation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

A natural grouping of motifs with an aspartate or asparagine residue forming two hydrogen bonds to residues ahead in sequence: their occurrence at alpha-helical N termini and in other situations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Receptor and antibody epitopes in human growth hormone identified by homolog-scanning mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

A single arginine residue determines species specificity of the human growth hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Site-specific PEGylation of a lysine-deficient TNF-alpha with full bioactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

Darbepoetin alfa has a longer circulating half-life and greater in vivo potency than recombinant human erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

The effects of insulin-like growth factor-I (IGF-I), IGF-II and des(1–3)IGF-I, a potent IGF analogue, on growth hormone and IGF-binding protein secretion from cultured rat anterior pituitary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406092200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406092200

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8 December 2017

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