Molecular analysis of different FLT3-ITD mutations in acute myeloid leukemia (Q45024752)

8 December 2017

title

Molecular analysis of different FLT3-ITD mutations in acute myeloid leukemia (English)

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8 December 2017

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Olga Blau

1

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8 December 2017

Rimma Berenstein

series ordinal

2

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8 December 2017

Annette Sindram

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3

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8 December 2017

Igor Wolfgang Blau

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4

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8 December 2017

publication date

5 September 2012

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8 December 2017

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8 December 2017

volume

54

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8 December 2017

issue

1

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8 December 2017

page(s)

145-152

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Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

8 December 2017

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Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials.

21 January 2018

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Clinical outcome of de novo acute myeloid leukaemia patients with normal cytogenetics is affected by molecular genetic alterations: a concise review

21 January 2018

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Molecular diagnostics in acute leukemias

21 January 2018

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Prognostic implications of gene mutations in acute myeloid leukemia with normal cytogenetics

21 January 2018

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Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications

21 January 2018

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The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

21 January 2018

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Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

21 January 2018

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Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.

21 January 2018

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The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia

21 January 2018

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Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia

21 January 2018

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Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

21 January 2018

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The structural basis for autoinhibition of FLT3 by the juxtamembrane domain

21 January 2018

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Human CD34+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells.

21 January 2018

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Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways cooperate in mediating cytokine-induced proliferation of a leukemic cell line

21 January 2018

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Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling

21 January 2018

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Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD.

21 January 2018

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Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?

21 January 2018

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Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia

21 January 2018

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Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor

21 January 2018

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Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome.

21 January 2018

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Structural and numerical variation of FLT3/ITD in pediatric AML.

21 January 2018

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Size of FLT3 internal tandem duplication has prognostic significance in patients with acute myeloid leukemia

21 January 2018

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More on prognostic significance of FLT3/ITD size in acute myeloid leukemia (AML).

21 January 2018

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https://api.crossref.org/works/10.3109%2F10428194.2012.704999

The size of duplication does not add to the prognostic significance of FLT3 internal tandem duplication in acute myeloid leukemia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.704999

Arginine 595 is duplicated in patients with acute leukemias carrying internal tandem duplications of FLT3 and modulates its transforming potential.

21 January 2018

1 reference

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Report of the National Cancer Institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.3109%2F10428194.2012.704999

10.3109/10428194.2012.704999

21 January 2018

Identifiers

DOI

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8 December 2017

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