Uncoupling protein-3 sensitizes cells to mitochondrial-dependent stimulus of apoptosis. (Q45035017)

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1 January 2020

title

Uncoupling protein-3 sensitizes cells to mitochondrial-dependent stimulus of apoptosis (English)

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5

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1 January 2020

Yolanda Cámara

2

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1 January 2020

author name string

Laurent Dejean

1

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1 January 2020

Brigitte Sibille

3

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Gemma Solanes

4

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publication date

1 November 2004

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Journal of Cellular Physiology

1 January 2020

published in

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volume

201

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issue

2

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page(s)

294-304

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Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim the mitochondrion

1 January 2020

cites work

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Bcl-2 inhibits apoptosis induced by mitochondrial uncoupling but does not prevent mitochondrial transmembrane depolarization

21 January 2018

1 reference

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

21 January 2018

1 reference

Molecular mechanisms of apoptosis in the cardiac myocyte

21 January 2018

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Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression

21 January 2018

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Uncoupling protein-3 gene expression in skeletal muscle during development is regulated by nutritional factors that alter circulating non-esterified fatty acids.

21 January 2018

1 reference

Rotenone inhibits the mitochondrial permeability transition-induced cell death in U937 and KB cells

21 January 2018

1 reference

Uncoupling protein 2 prevents neuronal death including that occurring during seizures: a mechanism for preconditioning.

21 January 2018

1 reference

Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

21 January 2018

1 reference

Superoxide activates mitochondrial uncoupling proteins

21 January 2018

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Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

21 January 2018

1 reference

UCP2-dependent proton leak in isolated mammalian mitochondria

21 January 2018

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Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation By electron flow through the respiratory chain complex i.

21 January 2018

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Uncoupling of protein-3 induces an uncontrolled uncoupling of mitochondria after expression in muscle derived L6 cells

21 January 2018

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Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor beta in rat fetal hepatocytes

21 January 2018

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Dependence of permeability transition pore opening and cytochrome C release from mitochondria on mitochondria energetic status

21 January 2018

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Mitochondrial control of cell death

21 January 2018

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21 January 2018

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Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

21 January 2018

1 reference

Regulation of cellular oncosis by uncoupling protein 2.

21 January 2018

1 reference

The 'novel' 'uncoupling' proteins UCP2 and UCP3: what do they really do? Pros and cons for suggested functions.

21 January 2018

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Regulation of apoptosis by respiration: cytochrome c release by respiratory substrates

21 January 2018

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14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax

21 January 2018

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Uncoupling proteins 2 and 3 interact with members of the 14.3.3 family

21 January 2018

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Mitochondria, the killer organelles and their weapons

21 January 2018

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The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP

21 January 2018

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Apoptosis of skeletal muscles during development and disease

21 January 2018

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Skeletal muscle uncoupling protein 3 (UCP3): mitochondrial uncoupling protein in search of a function

21 January 2018

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Modulation of apoptosis by mitochondrial uncouplers: apoptosis-delaying features despite intrinsic cytotoxicity

21 January 2018

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Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis

21 January 2018

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14-3-3 proteins: key regulators of cell division, signalling and apoptosis.

21 January 2018

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UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue

21 January 2018

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Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator

21 January 2018

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Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types.

21 January 2018

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Gene microarray identification of redox and mitochondrial elements that control resistance or sensitivity to apoptosis

21 January 2018

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Activating omega-6 polyunsaturated fatty acids and inhibitory purine nucleotides are high affinity ligands for novel mitochondrial uncoupling proteins UCP2 and UCP3.

21 January 2018

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Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

21 January 2018

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Cytochrome c-mediated apoptosis in cells lacking mitochondrial DNA. Signaling pathway involving release and caspase 3 activation is conserved

21 January 2018

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