Targeting of NPC1 to late endosomes involves multiple signals, including one residing within the putative sterol-sensing domain (Q45044200)

8 December 2017

Targeting of NPC1 to late endosomes involves multiple signals, including one residing within the putative sterol-sensing domain (English)

1 reference

8 December 2017

Catherine Scott

1

1 reference

8 December 2017

Maureen E Higgins

series ordinal

2

1 reference

8 December 2017

Joanna P Davies

series ordinal

3

1 reference

8 December 2017

Yiannis A Ioannou

series ordinal

4

1 reference

8 December 2017

language of work or name

English

0 references

publication date

3 September 2004

1 reference

Journal of Biological Chemistry

8 December 2017

1 reference

8 December 2017

279

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8 December 2017

46

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8 December 2017

48214-48223

1 reference

Signals for sorting of transmembrane proteins to endosomes and lysosomes

8 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Signal-dependent membrane protein trafficking in the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

The trans-Golgi network: a late secretory sorting station

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Lysosomal targeting of P-selectin is mediated by a novel sequence within its cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Sorting and targeting of melanosomal membrane proteins: signals, pathways, and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Niemann-Pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Niemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

A di-acidic signal required for selective export from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

A di-leucine sequence and a cluster of acidic amino acids are required for dynamic retention in the endosomal recycling compartment of fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Intracellular trafficking of lysosomal membrane proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Cysteine34 of the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor is reversibly palmitoylated and required for normal trafficking and lysosomal enzyme sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

A di-acidic (DXE) code directs concentration of cargo during export from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Identification of interdependent signals required for anterograde traffic of the ATP-binding cassette transporter protein Yor1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

An acidic sequence of a putative yeast Golgi membrane protein binds COPII and facilitates ER export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

ER transport signals and trafficking of potassium channels and receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Role of ER export signals in controlling surface potassium channel numbers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

A sequence motif responsible for ER export and surface expression of Kir2.0 inward rectifier K(+) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Efficient export of the vesicular stomatitis virus G protein from the endoplasmic reticulum requires a signal in the cytoplasmic tail that includes both tyrosine-based and di-acidic motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Distinct reading of different structural determinants modulates the dileucine-mediated transport steps of the lysosomal membrane protein LIMPII and the insulin-sensitive glucose transporter GLUT4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Molecular characterization of the di-leucine-based internalization motif of the T cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Polar transmembrane domains target proteins to the interior of the yeast vacuole

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Structural requirements for major histocompatibility complex class II invariant chain endocytosis and lysosomal targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Identification of a non-canonical tyrosine-based endocytic motif in an ionotropic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Recycling of furin from the plasma membrane. Functional importance of the cytoplasmic tail sorting signals and interaction with the AP-2 adaptor medium chain subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Rer1p, a retrieval receptor for endoplasmic reticulum membrane proteins, is dynamically localized to the Golgi apparatus by coatomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Rer1p, a retrieval receptor for ER membrane proteins, recognizes transmembrane domains in multiple modes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Distinct monoubiquitin signals in receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Identification of three internalization sequences in the cytoplasmic tail of the 46 kDa mannose 6-phosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

Analysis of the structural requirements for lysosomal membrane targeting using transferrin receptor chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

The Dileucine Motif Within the Tail of MPR46 is Required for Sorting of the Receptor in Endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406090200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406090200

1 reference

8 December 2017

1 reference