Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells. (Q45051064)

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1 January 2020

title

Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells (English)

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1 January 2020

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B-cell chronic lymphocytic leukemia

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1

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1 January 2020

author name string

P Pérez-Galán

2

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P Giraldo

3

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1 January 2020

N López-Royuela

4

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M Gómez-Benito

5

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1 January 2020

L Larrad

6

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1 January 2020

P Lasierra

7

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D Rubio-Félix

8

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A Anel

9

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J Naval

10

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publication date

1 October 2004

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1 January 2020

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1 January 2020

volume

18

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issue

10

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page(s)

1599-1604

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A systematic overview of chemotherapy effects in B-cell chronic lymphocytic leukaemia

1 January 2020

cites work

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Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia

21 January 2018

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Farnesyl transferase inhibitors in clinical development

21 January 2018

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Design of growth factor antagonists with antiangiogenic and antitumor properties

21 January 2018

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A one-step DGGE scanning method for detection of mutations in the K-, N-, and H-ras oncogenes: mutations at codons 12, 13 and 61 are rare in B-cell non-Hodgkin's lymphoma.

21 January 2018

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Absence of Kirsten-ras oncogene activation in B-cell chronic lymphocytic leukemia

21 January 2018

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Analysis of RAS oncogene mutations in human lymphoid malignancies

21 January 2018

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Involvement of protein kinase C and phosphatidylinositol 3-kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells.

21 January 2018

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Efficacy of the farnesyl transferase inhibitor R115777 in chronic myeloid leukemia and other hematologic malignancies

21 January 2018

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The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

21 January 2018

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Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

21 January 2018

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Activation of Bak, Bax, and BH3-only proteins in the apoptotic response to doxorubicin.

21 January 2018

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Caspase activation inhibits proteasome function during apoptosis

21 January 2018

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Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

21 January 2018

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Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

21 January 2018

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Transcriptional and translational control of Mcl-1 during apoptosis

21 January 2018

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Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis

21 January 2018

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Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cdelta.

21 January 2018

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Chronic lymphocytic leukemia: case-based session

21 January 2018

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7 January 2021

Chronic lymphocytic leukemia

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7 January 2021

Opinion: Searching for the elusive targets of farnesyltransferase inhibitors

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7 January 2021

Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c

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7 January 2021

Protease Involvement in Fodrin Cleavage and Phosphatidylserine Exposure in Apoptosis

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7 January 2021

Caspases influence the mode but not the extent of cell death induced by purine analogues in chronic lymphocytic leukaemia

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403469

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356656%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 January 2020

1052077157

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