TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like (Q45053976)

9 December 2017

title

TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like (English)

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9 December 2017

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5

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9 December 2017

4

Douglas T Golenbock

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9 December 2017

1

Jakub Siednienko

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9 December 2017

Annett Halle

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9 December 2017

Kamalpreet Nagpal

series ordinal

3

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9 December 2017

language of work or name

English

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publication date

19 October 2010

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European Journal of Immunology

9 December 2017

published in

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9 December 2017

volume

40

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9 December 2017

issue

11

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9 December 2017

page(s)

3150-3160

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Lack of essential role of NF-kappa B p50, RelA, and cRel subunits in virus-induced type 1 IFN expression

9 December 2017

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Adenoviral gene transfer into osteoarthritis synovial cells using the endogenous inhibitor IkappaBalpha reveals that most, but not all, inflammatory and destructive mediators are NFkappaB dependent.

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Toll-like receptor signalling

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MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3.

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

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Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88.

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MyD88 functions as a negative regulator of TLR3/TRIF-induced corneal inflammation by inhibiting activation of c-Jun N-terminal kinase

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Interferon gene regulation: not all roads lead to Tolls

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TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

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Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

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7 January 2021

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7 January 2021

Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways

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7 January 2021

Multiple regulatory domains control IRF-7 activity in response to virus infection

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7 January 2021

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

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7 January 2021

Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: assignment of a type I interferon signature in a subpopulation of patients.

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7 January 2021

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

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7 January 2021

TIRAP: an adapter molecule in the Toll signaling pathway

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7 January 2021

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

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7 January 2021

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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7 January 2021

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

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7 January 2021

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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7 January 2021

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

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7 January 2021

A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.

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7 January 2021

Identifiers

DOI

10.1002/EJI.201040547

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9 December 2017

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