Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor (Q45058154)

9 December 2017

title

Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor (English)

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9 December 2017

7

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9 December 2017

Ian J Jackson

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Sally H Cross

object named as

Sally H Cross

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Daekee Lee

object named as

Daekee Lee

1

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author name string

Karen E Strunk

3

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9 December 2017

Joanne E Morgan

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9 December 2017

Candice L Bailey

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9 December 2017

publication date

1 July 2004

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9 December 2017

number of pages

12

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inferred from page(s)

published in

Mammalian Genome

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9 December 2017

volume

15

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9 December 2017

issue

7

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9 December 2017

page(s)

525-536

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Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development

9 December 2017

cites work

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12 December 2020

Spectrum of Bmp5 mutations from germline mutagenesis experiments in mice

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12 December 2020

Genomic, transcriptional and mutational analysis of the mouse microphthalmia locus

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12 December 2020

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

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12 December 2020

Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells

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12 December 2020

Active and inactive protein kinases: structural basis for regulation

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12 December 2020

Novel ENU-induced eye mutations in the mouse: models for human eye disease

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12 December 2020

Mom1 is a semi-dominant modifier of intestinal adenoma size and multiplicity in Min/+ mice

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12 December 2020

Mice harboring a defective epidermal growth factor receptor (waved-2) have an increased susceptibility to acute dextran sulfate-induced colitis

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12 December 2020

Nucleotide-binding properties of kinase-deficient epidermal-growth-factor-receptor mutants

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12 December 2020

The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit

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12 December 2020

Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

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12 December 2020

Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis

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12 December 2020

Importance of functional EGF receptors in recovery from acute nephrotoxic injury.

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12 December 2020

New insights into the assembly of extracellular microfibrils from the analysis of the fibrillin 1 mutation in the tight skin mouse

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12 December 2020

Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis

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12 December 2020

Mouse mutants from chemically mutagenized embryonic stem cells

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12 December 2020

Type I growth factor receptors: current status and future work.

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12 December 2020

Epidermal growth factor activates reproductive behavior independent of ovarian steroids in female rodents

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12 December 2020

Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase family

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12 December 2020

An allelic series of mutations in the kit ligand gene of mice. I. Identification of point mutations in seven ethylnitrosourea-induced Kitl(Steel) alleles

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12 December 2020

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

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12 December 2020

Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation.

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12 December 2020

The conformational plasticity of protein kinases

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12 December 2020

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

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12 December 2020

Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms.

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12 December 2020

Genetics of dark skin in mice

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12 December 2020

Deceiving appearances: signaling by "dead" and "fractured" receptor protein-tyrosine kinases

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12 December 2020

Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential

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12 December 2020

TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice.

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12 December 2020

The internalization and endosomal trafficking of the EGF receptor in response to EGF is delayed in the waved-2 mouse liver

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12 December 2020

Epidermal growth factor stimulates tyrosine phosphorylation in the neonatal mouse: association of a M(r) 55,000 substrate with the receptor

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12 December 2020

Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

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12 December 2020

Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family

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12 December 2020

Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis

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12 December 2020

Molecular cloning and expression of an additional epidermal growth factor receptor-related gene

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12 December 2020

A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation

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12 December 2020

Phenotypic variation resulting from a deficiency of epidermal growth factor receptor in mice is caused by extensive genetic heterogeneity that can be genetically and molecularly partitioned

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12 December 2020

Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism

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12 December 2020

Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors

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12 December 2020

Genetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammals

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12 December 2020

Activating mutations for the met tyrosine kinase receptor in human cancer

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12 December 2020

Strain-dependent epithelial defects in mice lacking the EGF receptor

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12 December 2020

The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase

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12 December 2020

Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development

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12 December 2020

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

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12 December 2020

Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II

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12 December 2020

A kinase-negative epidermal growth factor receptor that retains the capacity to stimulate DNA synthesis

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12 December 2020

The antimorphic nature of the Tc allele at the mouse T locus

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12 December 2020

Supermutagenicity of ethylnitrosourea in the mouse spot test: comparisons with methylnitrosourea and ethylnitrosourethane

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12 December 2020

Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure

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12 December 2020

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

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12 December 2020

A defective EGF-receptor in waved-2 mice attenuates intestinal adaptation

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12 December 2020

10.1007/S00335-004-2384-2

Identifiers

DOI

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Dimensions Publication ID

9 December 2017

1003769033

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