The role of muscarinic cholinergic receptors in the discriminative stimulus properties of clozapine in rats (Q45106222)

9 December 2017

The role of muscarinic cholinergic receptors in the discriminative stimulus properties of clozapine in rats (English)

1 reference

9 December 2017

Kelley BM

1

1 reference

PubMed ID

9258998

9 December 2017

Porter JH

series ordinal

2

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PubMed ID

9258998

9 December 2017

language of work or name

English

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publication date

1 August 1997

1 reference

Pharmacology, Biochemistry and Behavior

9 December 2017

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9 December 2017

57

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9 December 2017

4

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9 December 2017

707-719

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Clozapine. A novel antipsychotic agent

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Clozapine is a potent and selective muscarinic antagonist at the five cloned human muscarinic acetylcholine receptors expressed in CHO-K1 cells

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Clozapine attenuates the discriminative stimulus properties of (-)-nicotine.

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Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sites

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Clozapine: neuroleptic-induced EPS and tardive dyskinesia

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Heterogeneity of histamine H1-receptors: species variations in [3H]mepyramine binding of brain membranes

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Biochemical and behavioural properties of clozapine

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Characterization of muscarinic cholinergic receptors in cat tracheal gland cells

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Characterization of BIBN 99: a lipophilic and selective muscarinic M2 receptor antagonist

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Ritanserin, a selective 5-HT2/1C antagonist, and negative symptoms in schizophrenia. A placebo-controlled double-blind trial

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Treatment of schizophrenia: a clinical and preclinical evaluation of neuroleptic drugs

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Inter-animal olfactory cues in operant drug discrimination procedures in rats.

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Muscarinic M1, M2 receptor binding. Relationship with functional efficacy

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The binding of some antidepressant drugs to brain muscarinic acetylcholine receptors

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The benzodiazepine receptor antagonist flumazenil increases acetylcholine release in rat hippocampus.

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Discriminative stimulus properties of muscarinic agonists.

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Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine

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Mianserin as a discriminative stimulus in rats: asymmetrical cross-generalization with scopolamine

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Antagonism of oxotremorine-induced behavioral suppression by antimuscarinic drugs.

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Interactions of clozapine, thioridazine, and mezilamine with oxotremorine on schedule-controlled responding

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Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors

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Non-selectivity of amitriptyline for subtypes of brain muscarinic receptors demonstrated in binding and functional assays

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Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia

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The interaction of clozapine with dopamine D1 versus dopamine D2 receptor-mediated function: behavioural indices

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7 January 2021

Cholinergic mediation of the discriminative stimulus properties of clozapine.

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Discriminable effects of antimuscarinics: Dose response and substitution test studies

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Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

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Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

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Interaction of psychotropic drugs with brain muscarinic cholinoceptors: similarities of biperiden with pirenzepine in receptor binding properties.

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7 January 2021

Cholinergic hyperactivity and negative schizophrenic symptoms. A model of cholinergic/dopaminergic interactions in schizophrenia

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Discriminative stimulus properties of physostigmine in rats

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Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

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Serotonergic drugs do not substitute for clozapine in clozapine-trained rats in a two-lever drug discrimination procedure

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7 January 2021

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Identifiers

DOI

1 reference

9 December 2017

1 reference

PubMed ID

9258998