Differential mutagenicity of riddelliine in liver endothelial and parenchymal cells of transgenic big blue rats (Q45110043)

2 July 2019

title

Differential mutagenicity of riddelliine in liver endothelial and parenchymal cells of transgenic big blue rats (English)

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2 July 2019

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author name string

Ming W Chou

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Peter P Fu

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Robert H Heflich

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Tao Chen

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language of work or name

English

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publication date

1 November 2004

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2 July 2019

published in

Cancer Letters

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volume

215

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issue

2

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page(s)

151-158

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Somatic mutation in the mammary gland: influence of time and estrus

cites work

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12 December 2020

Corn oil rapidly activates nuclear factor-kappaB in hepatic Kupffer cells by oxidant-dependent mechanisms.

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12 December 2020

Metabolic activation of the tumorigenic pyrrolizidine alkaloid, riddelliine, leading to DNA adduct formation in vivo

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12 December 2020

Epithelial and fibroblast cell lines cultured from the transgenic BigBlue rat: an in vitro mutagenesis assay

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12 December 2020

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mutagenesis in cultured Big Blue rat mammary epithelial and fibroblast cells.

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12 December 2020

Mutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic rats

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12 December 2020

The hepatic endothelial carcinogen riddelliine induces endothelial apoptosis, mitosis, S phase, and p53 and hepatocytic vascular endothelial growth factor expression after short-term exposure.

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12 December 2020

Human Liver Microsomal Metabolism and DNA Adduct Formation of the Tumorigenic Pyrrolizidine Alkaloid, Riddelliine

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12 December 2020

Correlation of DNA adduct formation and riddelliine-induced liver tumorigenesis in F344 rats and B6C3F(1) mice

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12 December 2020

Toxicology and carcinogenesis studies of riddelliine (CAS No. 23246-96-0) in F344/N rats and B6C3F1 mice (gavage studies).

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12 December 2020

Toxicity and carcinogenicity of riddelliine in rats and mice

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12 December 2020

Chemical-specific alterations in ras, p53, and beta-catenin genes in hemangiosarcomas from B6C3F1 mice exposed to o-nitrotoluene or riddelliine for 2 years

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12 December 2020

Pyrrolizidine alkaloids--genotoxicity, metabolism enzymes, metabolic activation, and mechanisms

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12 December 2020

Application of a statistical dynamic model investigating the short-term cellular kinetics induced by riddelliine, a hepatic endothelial carcinogen

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12 December 2020

Mutations induced by the carcinogenic pyrrolizidine alkaloid riddelliine in the liver cII gene of transgenic big blue rats.

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12 December 2020

Statistical test for the comparison of samples from mutational spectra

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12 December 2020

Cell specificity in hepatocarcinogenesis: preferential accumulation of O6-methylguanine in target cell DNA during continuous exposure to rats to 1,2-dimethylhydrazine.

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12 December 2020

Differential repair of O(6)-methylguanine in DNA of rat hepatocytes and nonparenchymal cells.

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12 December 2020

Software for the analysis of mutations at the human hprt gene

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12 December 2020

Toxicity and carcinogenicity of riddelliine following 13 weeks of treatment to rats and mice

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12 December 2020

10.1016/J.CANLET.2004.06.013

Identifiers

DOI

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2 July 2019

PMC publication ID

6370022

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2 July 2019

PubMed publication ID

15488633

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2 July 2019