Phosphorylated CXCR4 is associated with poor survival in adults with B-acute lymphoblastic leukemia (Q45116919)

9 December 2017

title

Phosphorylated CXCR4 is associated with poor survival in adults with B-acute lymphoblastic leukemia (English)

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9 December 2017

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6

Hagop M Kantarjian

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9

Marina Konopleva

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Michael Andreeff

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Jeffrey L Jorgensen

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Sergej Konoplev

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L Jeffrey Medeiros

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Deborah A Thomas

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E Lin

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4

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Jan Burger

series ordinal

5

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language of work or name

English

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publication date

31 March 2011

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volume

117

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issue

20

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page(s)

4689-4695

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9 December 2017

cites work

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Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia

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CXCR4 is a prognostic marker in acute myelogenous leukemia.

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The biology and therapy of adult acute lymphoblastic leukemia

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Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.

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beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4

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Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation

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CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK.

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Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor

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7 January 2021

Chemokine receptor CXCR4 expression in breast cancer as a potential predictive marker of isolated tumor cells in bone marrow

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7 January 2021

Is high expression of the chemokine receptor CXCR-4 of predictive value for early relapse in childhood acute lymphoblastic leukaemia?

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7 January 2021

Cytogenetic findings in mantle cell lymphoma cases with a high level of peripheral blood involvement have a distinct pattern of abnormalities

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7 January 2021

Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype

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7 January 2021

Regulation of human chemokine receptors CXCR4. Role of phosphorylation in desensitization and internalization

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7 January 2021

CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment

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7 January 2021

Identifiers

DOI

10.1002/CNCR.26113

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9 December 2017

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