Sipholane triterpenoids: chemistry, reversal of ABCB1/P-glycoprotein-mediated multidrug resistance, and pharmacophore modeling. (Q45139303)

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31 January 2020

title

Sipholane triterpenoids: chemistry, reversal of ABCB1/P-glycoprotein-mediated multidrug resistance, and pharmacophore modeling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19534474%20AND%20SRC:MED&resulttype=core&format=json

(3S,5As,6S,7R,9aS)-6-[2-[(1S,3aS,5R,8aS)-1-hydroxy-1,4,4,6-tetramethyl-2,3,3a,5,8,8a-hexahydroazulen-5-yl]ethyl]-2,2,5a,7-tetramethyl-4,5,6,8,9,9a-hexahydro-3H-benzo[b]oxepine-3,7-diol

31 January 2020

main subject

multiple drug resistance

1 reference

based on heuristic

inferred from title

Callyspongia siphonella

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1 reference

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inferred from

reverse claim

(3S,4Z,4aS,8R,8aS)-4-[2-[(3S,5aS,6S,7S,9aS)-3,7-dihydroxy-2,2,5a-trimethyl-3,4,5,6,7,8,9,9a-octahydrobenzo[b]oxepin-6-yl]ethylidene]-8-hydroxy-3,5,5-trimethyl-1,4a,6,7,8,8a-hexahydronaphthalen-2-one

1 reference

1 reference

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Siphonellinol C-23-hydroperoxide

1 reference

1 reference

6-[2-(1,7-Dihydroxy-1,4,4,6-tetramethyl-1,2,3,3a,4,7,8,8a-octahydroazulen-5-yl)ethyl]-2,2,5a,7-tetramethyldecahydro-1-benzoxepine-3,7-diol

1 reference

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1

1 reference

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31 January 2020

Lamiaa A. Shaala

5

1 reference

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31 January 2020

Diaa Youssef

6

1 reference

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31 January 2020

author name string

Ioana Abraham

2

1 reference

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31 January 2020

Paulo Carvalho

3

1 reference

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31 January 2020

Ye-Hong Kuang

4

1 reference

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31 January 2020

Mitchell A Avery

7

1 reference

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31 January 2020

Zhe-Sheng Chen

8

1 reference

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31 January 2020

Khalid A El Sayed

9

1 reference

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Journal of Natural Products

31 January 2020

publication date

17 June 2009

1 reference

16 September 2022

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31 January 2020

volume

72

1 reference

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31 January 2020

issue

7

1 reference

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31 January 2020

page(s)

1291-1298

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