Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse (Q45174166)

10 December 2017

Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse (English)

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10 December 2017

G Kuriya

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T Uchida

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S Akazawa

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M Kobayashi

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K Nakamura

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T Satoh

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I Horie

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E Kawasaki

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H Yamasaki

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L Yu

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Y Iwakura

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H Sasaki

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Y Nagayama

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A Kawakami

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N Abiru

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23 May 2013

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56

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1773-1780

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8

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https://scigraph.springernature.com/pub.10.1007/s00125-013-2935-8

10 December 2017

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cites work

Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse

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Th1 to Th2 cytokine shifts in nonobese diabetic mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation.

21 January 2018

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Protection of nonobese diabetic mice from diabetes by gene(s) closely linked to IFN-gamma receptor loci.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-013-2935-8

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

21 January 2018

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A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

21 January 2018

1 reference

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IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2935-8

CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2935-8

Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-2935-8

Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice.

21 January 2018

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Plasticity of CD4+ T cell lineage differentiation.

21 January 2018

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Late developmental plasticity in the T helper 17 lineage

21 January 2018

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Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells.

21 January 2018

1 reference

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Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

21 January 2018

1 reference

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Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses

21 January 2018

1 reference

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B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

21 January 2018

1 reference

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Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes

21 January 2018

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Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes

21 January 2018

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Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

21 January 2018

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Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice.

21 January 2018

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Critical role of IFN-gamma in CFA-mediated protection of NOD mice from diabetes development

21 January 2018

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Heterogeneity and plasticity of T helper cells

21 January 2018

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Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy

21 January 2018

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IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells.

21 January 2018

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Epigenetic changes at Il12rb2 and Tbx21 in relation to plasticity behavior of Th17 cells

21 January 2018

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Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts.

21 January 2018

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IL-17 immunity in human type 1 diabetes

21 January 2018

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Cutting Edge: Increased IL-17-Secreting T Cells in Children with New-Onset Type 1 Diabetes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-013-2935-8

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

21 January 2018

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12 December 2020

IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes

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12 December 2020

IFN-gamma gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice.

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12 December 2020

Promotion of spontaneous diabetes in non-obese diabetes-prone mice by cyclophosphamide

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12 December 2020

Pancreas-infiltrating Th1 cells and diabetes develop in IL-12-deficient nonobese diabetic mice

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12 December 2020

Acceleration of the onset of diabetes in NOD mice by thymectomy at weaning

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12 December 2020

Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice

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12 December 2020

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

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12 December 2020

Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice

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12 December 2020

Diabetogenic T-cell clones

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12 December 2020

T Helper Type 17 Immune Response Plays an Indispensable Role for Development of Iodine-Induced Autoimmune Thyroiditis in Nonobese Diabetic-H2h4Mice

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12 December 2020

Protection of IFN-gamma signaling-deficient NOD mice from diabetes by cyclophosphamide

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12 December 2020

Prevention of type I diabetes in NOD mice by adjuvant immunotherapy

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12 December 2020

Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction

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12 December 2020

10.1007/S00125-013-2935-8

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Dimensions Publication ID

10 December 2017

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