Primer unblocking and rescue of DNA synthesis by azidothymidine (AZT)-resistant HIV-1 reverse transcriptase: comparison between initiation and elongation of reverse transcription and between (-) and (+) strand DNA synthesis (Q45177265)

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scientific article published on 18 March 2002

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English	Primer unblocking and rescue of DNA synthesis by azidothymidine (AZT)-resistant HIV-1 reverse transcriptase: comparison between initiation and elongation of reverse transcription and between (-) and (+) strand DNA synthesis	scientific article published on 18 March 2002

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scholarly article

1 reference

Europe PubMed Central

10 December 2017

Primer unblocking and rescue of DNA synthesis by azidothymidine (AZT)-resistant HIV-1 reverse transcriptase: comparison between initiation and elongation of reverse transcription and between (-) and (+) strand DNA synthesis (English)

1 reference

Europe PubMed Central

10 December 2017

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based on heuristic

inferred from title

5

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Europe PubMed Central

10 December 2017

author name string

Mickael Rigourd

1

1 reference

Europe PubMed Central

10 December 2017

Chantal Ehresmann

2

1 reference

Europe PubMed Central

10 December 2017

Michael A Parniak

3

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Europe PubMed Central

10 December 2017

Bernard Ehresmann

4

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Europe PubMed Central

10 December 2017

language of work or name

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publication date

18 March 2002

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Europe PubMed Central

10 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

10 December 2017

277

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Europe PubMed Central

10 December 2017

21

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Europe PubMed Central

10 December 2017

18611-18618

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Europe PubMed Central

10 December 2017

Antiretroviral therapy in adults: updated recommendations of the International AIDS Society-USA Panel

1 reference

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Analysis of inhibition of retroviral reverse transcriptase

1 reference

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Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Sensitivity of HIV-1 reverse transcriptase and its mutants to inhibition by azidothymidine triphosphate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase

1 reference

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21 January 2018

The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine

1 reference

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21 January 2018

Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides

1 reference

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21 January 2018

Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase

1 reference

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21 January 2018

Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

RNA dependent DNA replication fidelity of HIV-1 reverse transcriptase: evidence of discrimination between DNA and RNA substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Structural basis for the specificity of the initiation of HIV-1 reverse transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Inhibition of the initiation of HIV-1 reverse transcription by 3'-azido-3'-deoxythymidine. Comparison with elongation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

The emergence of different resistance mechanisms toward nucleoside inhibitors is explained by the properties of the wild type HIV-1 reverse transcriptase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

The crystal structure of HIV reverse-transcription primer tRNA(Lys,3) shows a canonical anticodon loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Dimerization of human immunodeficiency virus (type 1) RNA: stimulation by cations and possible mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunodeficiency virus type 1 replication

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Ordered appearance of human immunodeficiency virus type 1 nucleic acids following high multiplicity infection of macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

New substrates of DNA polymerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Contacts between Reverse Transcriptase and the Primer Strand Govern the Transition from Initiation to Elongation of HIV-1 Reverse Transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Initiation of reverse transcription of HIV-1: secondary structure of the HIV-1 RNA/tRNA(3Lys) (template/primer)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110836200

21 January 2018

Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M110836200

1 reference

Europe PubMed Central

10 December 2017

1 reference

Europe PubMed Central

10 December 2017

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