Differentiation of primary adult microglia alters their response to TLR8-mediated activation but not their capacity as APC. (Q45178138)

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6 January 2020

title

Differentiation of primary adult microglia alters their response to TLR8-mediated activation but not their capacity as APC (English)

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6 January 2020

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9

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Jeffrey Bajramovic

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6 January 2020

author name string

Ella A Zuiderwijk-Sick

1

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Céline van der Putten

2

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Malika Bsibsi

3

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Ilona P Deuzing

4

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Willem de Boer

5

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Carla Persoon-Deen

6

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Ivanela Kondova

7

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Leonie A Boven

8

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Bert A 't Hart

10

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Sandra Amor

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publication date

1 November 2007

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6 January 2020

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volume

55

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6 January 2020

issue

15

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6 January 2020

page(s)

1589-1600

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Broad expression of Toll-like receptors in the human central nervous system

6 January 2020

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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Isolation and characterization of adult microglial cells and oligodendrocytes derived from postmortem human brain tissue.

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Antigen presentation function of brain-derived dendriform cells depends on astrocyte help

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Functional dichotomy of mouse microglia developed in vitro: differential effects of macrophage and granulocyte/macrophage colony-stimulating factor on cytokine secretion and antitoxoplasmic activity

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Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii

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Differentiation driven by granulocyte-macrophage colony-stimulating factor endows microglia with interferon-gamma-independent antigen presentation function

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Toll-like receptor control of the adaptive immune responses

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TLR signaling tailors innate immune responses in human microglia and astrocytes

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Innate immune recognition

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Dap12 and Trem2, molecules involved in innate immunity and neurodegeneration, are co-expressed in the CNS.

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Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

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Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis

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7 January 2021

Role of inflammation in neurodegenerative diseases

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7 January 2021

A y chromosome associated factor in strain bxsb producing accelerated autoimmunity and lymphoproliferation

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7 January 2021

Microglia in diseases of the central nervous system

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7 January 2021

Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

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7 January 2021

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

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Immunocytochemical characterisation of the immune reaction in the central nervous system in multiple sclerosis. Possible role for microglia in lesion growth

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7 January 2021

Identifiers

DOI

10.1002/GLIA.20572

1 reference

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6 January 2020

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