A molecular mechanism for Lys49-phospholipase A2 activity based on ligand-induced conformational change. (Q45185592)

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6 January 2020

title

A molecular mechanism for Lys49-phospholipase A2 activity based on ligand-induced conformational change (English)

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6 January 2020

5

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André Luís Berteli Ambrósio

6 January 2020

1

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6 January 2020

Maria Cristina Nonato

2

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6 January 2020

Raghuvir K Arni

4

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6 January 2020

author name string

Heloísa S Selistre de Araújo

3

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6 January 2020

Charlotte L Ownby

6

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Dulce H F de Souza

7

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6 January 2020

Richard C Garratt

8

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language of work or name

English

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publication date

13 December 2004

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Journal of Biological Chemistry

6 January 2020

number of pages

10

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based on heuristic

inferred from page(s)

published in

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6 January 2020

volume

280

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issue

8

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page(s)

7326-7335

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Evolutionary relationships and implications for the regulation of phospholipase A2 from snake venom to human secreted forms.

6 January 2020

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cDNA cloning and sequence analysis of a lysine-49 phospholipase A2 myotoxin from Agkistrodon contortrix laticinctus snake venom

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Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom

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Active-site mutagenesis of a Lys49-phospholipase A2: biological and membrane-disrupting activities in the absence of catalysis

21 January 2018

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An overview of lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action

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Myotoxin II from Bothrops asper (Terciopelo) venom is a lysine-49 phospholipase A2.

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A SequenceSpace analysis of Lys49 phopholipases A2: clues towards identification of residues involved in a novel mechanism of membrane damage and in myotoxicity

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Crystallographic and spectroscopic characterization of a molecular hinge: conformational changes in bothropstoxin I, a dimeric Lys49-phospholipase A2 homologue.

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Immunochemical characterization and role in toxic activities of region 115-129 of myotoxin II, a Lys49 phospholipase A2 from Bothrops asper snake venom.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identifiers

DOI

10.1074/JBC.M410588200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15596433%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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