aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division. (Q45204952)

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11 February 2020

title

aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division (English)

1 reference

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Protein kinase C-like 3 CELE_F09E5.1

11 February 2020

main subject

phosphorylation

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1 reference

GOA release 2020-03-11

author

Albert J.R. Heck

6

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11 February 2020

Matilde Galli

1

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11 February 2020

Javier Munoz

2

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11 February 2020

5

Stephan W Grill

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11 February 2020

author name string

Vincent Portegijs

3

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11 February 2020

Mike Boxem

4

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11 February 2020

Sander van den Heuvel

7

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publication date

21 August 2011

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11 February 2020

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volume

13

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issue

9

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page(s)

1132-1138

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https://scigraph.springernature.com/pub.10.1038/ncb2315

11 February 2020

exact match

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cites work

Determination of the cleavage plane in early C. elegans embryos

1 reference

12 December 2020

Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos

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Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo

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Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases

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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

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Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization

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PAR-6 is a conserved PDZ domain-containing protein that colocalizes with PAR-3 in Caenorhabditis elegans embryos.

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The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division

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Identification of critical domains and putative partners for the Caenorhabditis elegans spindle component LIN-5.

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Single-copy insertion of transgenes in Caenorhabditis elegans

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par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

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Dynamic localization of LIN-5 and GPR-1/2 to cortical force generation domains during spindle positioning

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12 December 2020

Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos

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12 December 2020

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

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A casein kinase 1 and PAR proteins regulate asymmetry of a PIP(2) synthesis enzyme for asymmetric spindle positioning

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Coupling of cortical dynein and G alpha proteins mediates spindle positioning in Caenorhabditis elegans

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Stabilization of cell polarity by the C. elegans RING protein PAR-2.

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LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans

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Spindle orientation during asymmetric cell division

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MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

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Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins

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In vivo stable isotope labeling of fruit flies reveals post-transcriptional regulation in the maternal-to-zygotic transition

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Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions

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LET-99 inhibits lateral posterior pulling forces during asymmetric spindle elongation in C. elegans embryos

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PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos

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12 December 2020

The forces that position a mitotic spindle asymmetrically are tethered until after the time of spindle assembly

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12 December 2020

Asymmetric cell division: recent developments and their implications for tumour biology

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12 December 2020

A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function inC. elegans

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12 December 2020

Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans

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12 December 2020

Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo

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12 December 2020

Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics.

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12 December 2020

Polarization of the C. elegans embryo by RhoGAP-mediated exclusion of PAR-6 from cell contacts.

1 reference

12 December 2020

Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins

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12 December 2020

The let-99 gene is required for proper spindle orientation during cleavage of the C. elegans embryo

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12 December 2020

A protein domain-based interactome network for C. elegans early embryogenesis

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12 December 2020

Control of nuclear centration in the C. elegans zygote by receptor-independent Galpha signaling and myosin II.

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12 December 2020

Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans

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12 December 2020

Highly robust, automated, and sensitive online TiO2-based phosphoproteomics applied to study endogenous phosphorylation in Drosophila melanogaster.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCB2315

1 reference

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Dimensions Publication ID

11 February 2020

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1 reference