Wnt signaling pathway, a potential target for Alzheimer's disease treatment, is activated by a novel multitarget compound ASS234. (Q45205666)

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13 March 2020

title

Wnt signaling pathway, a potential target for Alzheimer's disease treatment, is activated by a novel multitarget compound ASS234 (English)

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13 March 2020

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Alejandro Romero Martínez

5

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13 March 2020

Javier Del Pino

1

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13 March 2020

author name string

Eva Ramos

2

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13 March 2020

Oscar M Bautista Aguilera

3

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13 March 2020

José Marco-Contelles

4

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publication date

8 April 2014

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CNS Neuroscience & Therapeutics

13 March 2020

published in

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volume

20

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13 March 2020

issue

6

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13 March 2020

page(s)

568-570

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Acetylcholinesterase-Abeta complexes are more toxic than Abeta fibrils in rat hippocampus: effect on rat beta-amyloid aggregation, laminin expression, reactive astrocytosis, and neuronal cell loss

13 March 2020

cites work

1 reference

12 December 2020

Acetylcholinesterase (AChE)--amyloid-beta-peptide complexes in Alzheimer's disease. the Wnt signaling pathway

1 reference

12 December 2020

The Wnt signaling pathway: aging gracefully as a protectionist?

1 reference

12 December 2020

Wnt signaling in neuroprotection and stem cell differentiation

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12 December 2020

Transcriptional up-regulation of antioxidant genes by PPARδ inhibits angiotensin II-induced premature senescence in vascular smooth muscle cells

1 reference

12 December 2020

Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of [...]

1 reference

12 December 2020

Wnt signaling: role in Alzheimer disease and schizophrenia

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12 December 2020

Effects of novel monoamine oxidases and cholinesterases targeting compounds on brain neurotransmitters and behavior in rat model of vascular dementia.

1 reference

12 December 2020

Multipotent, permeable drug ASS234 inhibits Aβ aggregation, possesses antioxidant properties and protects from Aβ-induced apoptosis in vitro

1 reference

12 December 2020

In vivo activation of Wnt signaling pathway enhances cognitive function of adult mice and reverses cognitive deficits in an Alzheimer's disease model.

1 reference

12 December 2020

Identifiers

DOI

10.1111/CNS.12269

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13 March 2020

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13 March 2020

PubMed publication ID

24712554

1 reference