The MHC class II transactivator (CIITA) mRNA stability is critical for the HLA class II gene expression in myelomonocytic cells. (Q45208367)

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6 January 2020

title

The MHC class II transactivator (CIITA) mRNA stability is critical for the HLA class II gene expression in myelomonocytic cells (English)

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6 January 2020

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6 January 2020

author name string

Andrea De Lerma Barbaro

1

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6 January 2020

Francesco A Procopio

2

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6 January 2020

Lorenzo Mortara

3

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6 January 2020

Giovanna Tosi

4

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6 January 2020

language of work or name

English

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publication date

1 February 2005

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European Journal of Immunology

6 January 2020

published in

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6 January 2020

volume

35

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6 January 2020

page(s)

603-611

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6 January 2020

issue

2

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Functional characterization of a non-AUUUA AU-rich element from the c-jun proto-oncogene mRNA: evidence for a novel class of AU-rich elements

6 January 2020

cites work

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Posttranscriptional regulation of IL-10 gene expression through sequences in the 3'-untranslated region.

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Rapid degradation of AU-rich element (ARE) mRNAs is activated by ribosome transit and blocked by secondary structure at any position 5' to the ARE.

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The biochemistry and cell biology of antigen processing and presentation

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The bare lymphocyte syndrome and the regulation of MHC expression

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aIr-1, a newly found locus on mouse chromosome 16 encoding a trans-acting activator factor for MHC class II gene expression

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Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

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GTP binding by class II transactivator: role in nuclear import

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7 January 2021

Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes

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7 January 2021

Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters

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7 January 2021

Enhancement of CIITA transcriptional function by ubiquitin

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7 January 2021

N-terminal destruction signals lead to rapid degradation of the major histocompatibility complex class II transactivator CIITA.

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7 January 2021

CpG DNA induces a class II transactivator-independent increase in class II MHC by stabilizing class II MHC mRNA in B lymphocytes

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7 January 2021

Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

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7 January 2021

Maturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression

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7 January 2021

Post-transcriptional regulation of gene expression by degradation of messenger RNAs

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7 January 2021

Generation of destabilized green fluorescent protein as a transcription reporter

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7 January 2021

Turnover and translation of in vitro synthesized messenger RNAs in transfected, normal cells

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7 January 2021

Regulation of ICAM-1 mRNA stability by cycloheximide: role of serine/threonine phosphorylation and protein synthesis

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7 January 2021

Protein kinase C activation by phorbol esters: do cysteine-rich regions and pseudosubstrate motifs play a role?

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7 January 2021

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

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7 January 2021

The cap-to-tail guide to mRNA turnover

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7 January 2021

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

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7 January 2021

Block of Stat-1 activation in macrophages phagocytosing bacteria causes reduced transcription of CIITA and consequent impaired antigen presentation.

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7 January 2021

Translation and the stability of mRNAs encoding the transferrin receptor and c-fos

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7 January 2021

Active suppression of the class II transactivator-encoding AIR-1 locus is responsible for the lack of major histocompatibility complex class II gene expression observed during differentiation from B cells to plasma cells

1 reference

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7 January 2021

Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants

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7 January 2021

Identifiers

DOI

10.1002/EJI.200425378

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15627980%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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