Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70. (Q45235059)

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scientific article published in June 2005

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English	Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70.	scientific article published in June 2005

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7 January 2020

Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70 (English)

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7 January 2020

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Stephen M Todryk

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7 January 2020

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Hakim A Djeha

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7 January 2020

Steven Pelech

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7 January 2020

Christopher J Wrighton

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7 January 2020

Alistair S Irvine

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7 January 2020

Andrew Mountain

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7 January 2020

Kai S Lipinski

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1 June 2005

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7 January 2020

Cancer Gene Therapy

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7 January 2020

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7 January 2020

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7 January 2020

560-571

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The expression of bacterial nitroreductase in transgenic mice results in specific cell killing by the prodrug CB1954.

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Nitroreductase-mediated cell ablation is very rapid and mediated by a p53-independent apoptotic pathway

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Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression

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7 January 2020

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