Compound-specific Na+ channel pore conformational changes induced by local anaesthetics (Q45242246)

11 December 2017

title

Compound-specific Na+ channel pore conformational changes induced by local anaesthetics (English)

1 reference

11 December 2017

Koji Fukuda

1

1 reference

11 December 2017

Tadashi Nakajima

series ordinal

2

1 reference

11 December 2017

Prakash C Viswanathan

series ordinal

3

1 reference

11 December 2017

Jeffrey R Balser

series ordinal

4

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11 December 2017

language of work or name

English

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publication date

27 January 2005

1 reference

11 December 2017

published in

Journal of Physiology

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11 December 2017

volume

564

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11 December 2017

issue

Pt 1

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11 December 2017

page(s)

21-31

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A quantitative description of membrane current and its application to conduction and excitation in nerve

11 December 2017

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27 August 2018

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27 August 2018

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Slow inactivation does not block the aqueous accessibility to the outer pore of voltage-gated Na channels

27 August 2018

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27 August 2018

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27 August 2018

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A critical residue for isoform difference in tetrodotoxin affinity is a molecular determinant of the external access path for local anesthetics in the cardiac sodium channel

27 August 2018

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27 August 2018

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Ultra-slow inactivation in mu1 Na+ channels is produced by a structural rearrangement of the outer vestibule

27 August 2018

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Molecular dynamics of the sodium channel pore vary with gating: interactions between P-segment motions and inactivation.

27 August 2018

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27 August 2018

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27 August 2018

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27 August 2018

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Altered ionic selectivity of the sodium channel revealed by cysteine mutations within the pore

27 August 2018

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Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels

27 August 2018

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27 August 2018

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External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels.

27 August 2018

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27 August 2018

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27 August 2018

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Molecular determinants of state-dependent block of Na+ channels by local anesthetics

27 August 2018

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Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels

27 August 2018

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An engineered cysteine in the external mouth of a K+ channel allows inactivation to be modulated by metal binding

27 August 2018

1 reference

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On the molecular nature of the lidocaine receptor of cardiac Na+ channels. Modification of block by alterations in the alpha-subunit III-IV interdomain

27 August 2018

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Relative Sodium Current Block by Bupivacaine and Lidocaine in Neonatal Rat Myocytes

27 August 2018

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27 August 2018

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The Effects of External Potassium and Long Duration Voltage Conditioning on the Amplitude of Sodium Currents in the Giant Axon of the Squid, Loligo pealei

27 August 2018

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27 August 2018

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Inhibition of sodium currents by local anesthetics in chloramine-T-treated squid axons. The role of channel activation

27 August 2018

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Na channel activation gate modulates slow recovery from use-dependent block by local anesthetics in squid giant axons

27 August 2018

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Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels

27 August 2018

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Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region.

27 August 2018

1 reference

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A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

27 August 2018

1 reference

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Calcium channel characteristics conferred on the sodium channel by single mutations

27 August 2018

1 reference

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Mechanism of frequency-dependent inhibition of sodium currents in frog myelinated nerve by the lidocaine derivative GEA

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456037

Local anesthetic block of sodium channels in normal and pronase-treated squid giant axons

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456037

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456037

Mechanism for Bupivacaine Depression of Cardiac Conduction

27 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2004.081646

Depth asymmetries of the pore-lining segments of the Na+ channel revealed by cysteine mutagenesis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15677685

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2004.081646

1 reference

release_cfao3erqf5f2rbdhgy2dj5dt3e

11 December 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cfao3erqf5f2rbdhgy2dj5dt3e

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

1456037

0 references

1 reference