Mass Spectrometry Analysis of Wild-Type and Knock-in Q140/Q140 Huntington's Disease Mouse Brains Reveals Changes in Glycerophospholipids Including Alterations in Phosphatidic Acid and Lyso-Phosphatidic Acid (Q45290192)

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scientific article published in July 2015

Language	Label	Description	Also known as
English	Mass Spectrometry Analysis of Wild-Type and Knock-in Q140/Q140 Huntington's Disease Mouse Brains Reveals Changes in Glycerophospholipids Including Alterations in Phosphatidic Acid and Lyso-Phosphatidic Acid	scientific article published in July 2015

Statements

scholarly article

1 reference

Europe PubMed Central

11 December 2017

Mass Spectrometry Analysis of Wild-Type and Knock-in Q140/Q140 Huntington's Disease Mouse Brains Reveals Changes in Glycerophospholipids Including Alterations in Phosphatidic Acid and Lyso-Phosphatidic Acid (English)

1 reference

Europe PubMed Central

11 December 2017

Huntington's disease

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glycerophospholipids

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1

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Europe PubMed Central

11 December 2017

Ghazaleh Sadri-Vakili

7

object named as

Ghazaleh Sadri-Vakili

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Europe PubMed Central

11 December 2017

author name string

Shunyan Mo

2

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Europe PubMed Central

11 December 2017

Adelaide Tousley

3

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Europe PubMed Central

11 December 2017

Karin M Green

4

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Europe PubMed Central

11 December 2017

Ellen Sapp

5

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Europe PubMed Central

11 December 2017

Maria Iuliano

6

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Europe PubMed Central

11 December 2017

Scott A Shaffer

8

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Europe PubMed Central

11 December 2017

Neil Aronin

9

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Europe PubMed Central

11 December 2017

Marian DiFiglia

10

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Europe PubMed Central

11 December 2017

Kimberly B Kegel-Gleason

11

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Europe PubMed Central

11 December 2017

publication date

1 July 2015

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Europe PubMed Central

11 December 2017

Journal of Huntington's Disease

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Europe PubMed Central

11 December 2017

4

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Europe PubMed Central

11 December 2017

2

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Europe PubMed Central

11 December 2017

187-201

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Europe PubMed Central

11 December 2017

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

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https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Huntingtin associates with acidic phospholipids at the plasma membrane

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https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Interaction of huntingtin fragments with brain membranes--clues to early dysfunction in Huntington's disease

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https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Polyglutamine expansion in huntingtin alters its interaction with phospholipids

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https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

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https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Membrane interactions of the amphipathic amino terminus of huntingtin

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https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Phosphoinositides in cell regulation and membrane dynamics

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Direct and potent regulation of gamma-secretase by its lipid microenvironment

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Comparative lipidomic analysis of mouse and human brain with Alzheimer disease.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Plasma phospholipids identify antecedent memory impairment in older adults.

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https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

HD CAG-correlated gene expression changes support a simple dominant gain of function

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Altered cholesterol and fatty acid metabolism in Huntington disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Phosphoethanolamine and ethanolamine are decreased in Alzheimer's disease and Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Chorea-acanthocytosis: Abnormal composition of covalently bound fatty acids of erythrocyte membrane proteins

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Impaired phospholipid-related signal transduction in advanced Huntington's disease.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Polyglutamine expansion in huntingtin increases its insertion into lipid bilayers

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https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Curvature enhances binding and aggregation of huntingtin at lipid membranes

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https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Reagents that block neuronal death from Huntington's disease also curb oxidative stress

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR)

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

The multiple activities of CtBP/BARS proteins: the Golgi view

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

CtBP1/BARS is an activator of phospholipase D1 necessary for agonist-induced macropinocytosis

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Differential spatial expression and subcellular localization of CtBP family members in rodent brain.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Diacylglycerol kinases in the regulation of dendritic spines

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with alpha-synuclein genotype

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Generation of membrane diversity by lysophospholipid acyltransferases

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin toxicity

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

The synaptic ribbon is a site of phosphatidic acid generation in ribbon synapses.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Endophilin and CtBP/BARS are not acyl transferases in endocytosis or Golgi fission

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

A Golgi and ultrastructural study of the monkey globus pallidus.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Synaptic organization of the globus pallidus

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

A novel lysophosphatidic acid acyltransferase enzyme (LPAAT4) with a possible role for incorporating docosahexaenoic acid into brain glycerophospholipids

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Hepatoma-derived growth factor represses SET and MYND domain containing 1 gene expression through interaction with C-terminal binding protein

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

PLD regulates myoblast differentiation through the mTOR-IGF2 pathway

1 reference

https://api.crossref.org/works/10.3233%2FJHD-150149

21 January 2018

Identifiers

10.3233/JHD-150149

1 reference

Europe PubMed Central

11 December 2017

1 reference

Europe PubMed Central

11 December 2017

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