Huntingtin: a single bait hooks many species (Q45296265)

11 December 2017

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title

Huntingtin: a single bait hooks many species (English)

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11 December 2017

1

J F Gusella

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11 December 2017

M E MacDonald

2

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11 December 2017

1 June 1998

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Current Opinion in Neurobiology

11 December 2017

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11 December 2017

8

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11 December 2017

425-430

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11 December 2017

3

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Huntington's disease. Pathogenesis and management

11 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Neuropathological classification of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Neurobiology of Huntington's disease

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https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Comparative sequence analysis of the human and pufferfish Huntington's disease genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

HEAT repeats in the Huntington's disease protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Heterogeneous topographic and cellular distribution of huntingtin expression in the normal human neostriatum.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Characterization and localization of the Huntington disease gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Widespread expression of Huntington's disease gene (IT15) protein product

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin localization in brains of normal and Huntington's disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntington's disease gene product, huntingtin, associates with microtubules in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Inactivation of the mouse Huntington's disease gene homolog Hdh

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

A huntingtin-associated protein enriched in brain with implications for pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Interaction of huntingtin-associated protein with dynactin P150Glued

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

MOP2(SLA2) Affects the Abundance of the Plasma Membrane H+-ATPase ofSaccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

End4p/Sla2p interacts with actin-associated proteins for endocytosis in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Murine erythroleukemia cells possess an active ubiquitin- and ATP-dependent proteolytic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Characterization of a novel protein-binding module--the WW domain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Structure and function of the WW domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

The dodo gene family encodes a novel protein involved in signal transduction and protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Alpha-adaptin, a marker for endocytosis, is expressed in complex patterns during Drosophila development.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Symplekin, a novel type of tight junction plaque protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin interacts with cystathionine beta-synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Identification and tissue distribution of human cystathionine beta-synthase mRNA isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2898%2980071-8

7 January 2021

10.1016/S0959-4388(98)80071-8

Identifiers

DOI

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11 December 2017

1 reference

PubMed ID

9687360