Paradoxical function of orexin/hypocretin circuits in a mouse model of Huntington's disease (Q45301748)

22 February 2018

title

Paradoxical function of orexin/hypocretin circuits in a mouse model of Huntington's disease (English)

1 reference

22 February 2018

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3

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PubMed publication ID

11 December 2017

2

A Jennifer Morton

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22 February 2018

author name string

Rhîannan H Williams

series ordinal

1

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22 February 2018

publication date

13 February 2011

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22 February 2018

published in

Neurobiology of Disease

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22 February 2018

volume

42

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22 February 2018

issue

3

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22 February 2018

page(s)

438-445

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22 February 2018

Identifying sleep disturbances in Huntington's disease using a simple disease-focused questionnaire

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Normal huntingtin function: an alternative approach to Huntington's disease

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Fos expression in orexin neurons varies with behavioral state.

25 May 2018

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Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

25 May 2018

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Neurons containing hypocretin (orexin) project to multiple neuronal systems

25 May 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

25 May 2018

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

25 May 2018

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25 May 2018

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25 May 2018

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Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions

25 May 2018

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Increased neurotransmitter release at the neuromuscular junction in a mouse model of polyglutamine disease

25 May 2018

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Asymptomatic sleep abnormalities are a common early feature in patients with Huntington's disease

15 August 2018

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Disruption of peripheral circadian timekeeping in a mouse model of Huntington's disease and its restoration by temporally scheduled feeding

15 August 2018

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Management of sleep/wake cycles improves cognitive function in a transgenic mouse model of Huntington's disease

15 August 2018

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Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice.

15 August 2018

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The effects of modafinil on mood and cognition in Huntington's disease

15 August 2018

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Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease.

15 August 2018

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Hypocretin-1 (orexin A) levels are normal in Huntington's disease

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

CSF hypocretin levels are normal in Huntington's disease patients

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

Normal hypocretin-1 (orexin-A) levels in the cerebrospinal fluid of patients with Huntington's disease

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

The wake-promoting hypocretin/orexin neurons change their response to noradrenaline after sleep deprivation.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ.

15 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

Orexin loss in Huntington's disease.

15 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

Regulation of orexin neurons by the monoaminergic and cholinergic systems.

15 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

The wake-promoting hypocretin-orexin neurons are in an intrinsic state of membrane depolarization.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

Effects of lateral hypothalamic lesion with the neurotoxin hypocretin-2-saporin on sleep in Long-Evans rats

15 August 2018

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Diurnal and nocturnal rodents show rhythms in orexinergic neurons

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

15 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767114

Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation.

15 August 2018

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High Fos expression during the active phase in orexin neurons of a diurnal rodent, Tamias sibiricus barberi

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21324360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Membrane properties of histaminergic tuberomammillary neurones of the rat hypothalamus in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21324360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The brain histamine system in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21324360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NBD.2011.02.006

1 reference

22 February 2018

PMC publication ID

5767114

1 reference

22 February 2018

PubMed publication ID

21324360

1 reference

22 February 2018