Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics (Q45328178)

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scientific article published on 10 April 2013

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English	Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics	scientific article published on 10 April 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

RNA-binding proteins

1 reference

based on heuristic

inferred from title

5

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

author name string

Adel Amirouche

1

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Helina Tadesse

2

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

John A Lunde

3

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Guy Bélanger

4

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Bernard J Jasmin

6

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Europe PubMed Central

PubMed publication ID

13 December 2017

publication date

10 April 2013

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Europe PubMed Central

PubMed publication ID

13 December 2017

Human Molecular Genetics

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Europe PubMed Central

PubMed publication ID

13 December 2017

22

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Europe PubMed Central

PubMed publication ID

13 December 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

3093-3111

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Europe PubMed Central

PubMed publication ID

13 December 2017

Isolation of candidate cDNAs for portions of the Duchenne muscular dystrophy gene

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The value of mammalian models for duchenne muscular dystrophy in developing therapeutic strategies

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Molecular, cellular, and pharmacological therapies for Duchenne/Becker muscular dystrophies.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Dystrophin, its interactions with other proteins, and implications for muscular dystrophy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Dystrophin-glycoprotein complex: post-translational processing and dystroglycan function.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Diagnosis and cell-based therapy for Duchenne muscular dystrophy in humans, mice, and zebrafish

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Viral-mediated gene therapy for the muscular dystrophies: successes, limitations and recent advances

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Impending therapies for Duchenne muscular dystrophy

1 reference

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21 January 2018

Genetic therapeutic approaches for Duchenne muscular dystrophy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Molecular and functional analysis of the utrophin promoter

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Sp1 and Sp3 physically interact and co-operate with GABP for the activation of the utrophin promoter

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Activation of utrophin promoter by heregulin via the ets-related transcription factor complex GA-binding protein alpha/beta

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Therapeutics for Duchenne muscular dystrophy: current approaches and future directions.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Dystrophin: more than just the sum of its parts

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Biology of the striated muscle dystrophin-glycoprotein complex

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Progress in therapy for Duchenne muscular dystrophy.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Therapeutic approaches to muscular dystrophy.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Utrophin upregulation for treating Duchenne or Becker muscular dystrophy: how close are we?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

CT-GalNAc transferase overexpression in adult mice is associated with extrasynaptic utrophin in skeletal muscle fibres

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Calcineurin-NFAT signaling, together with GABP and peroxisome PGC-1{alpha}, drives utrophin gene expression at the neuromuscular junction.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Differential expression of utrophin-A and -B promoters in the central nervous system (CNS) of normal and dystrophic mdx mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Distinct regions in the 3' untranslated region are responsible for targeting and stabilizing utrophin transcripts in skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Translational regulation of utrophin by miRNAs

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

A cell-based high-throughput screening assay for posttranscriptional utrophin upregulation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Decoding ARE-mediated decay: is microRNA part of the equation?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

RNA-binding proteins and gene regulation in myogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Modulation of mRNA stability as a novel therapeutic approach

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Regulation of C2C12 myogenic terminal differentiation by MKK3/p38alpha pathway

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Muscle and neural isoforms of agrin increase utrophin expression in cultured myotubes via a transcriptional regulatory mechanism

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Ets-2 repressor factor silences extrasynaptic utrophin by N-box mediated repression in skeletal muscle

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Cooperation between myogenic regulatory factors and SIX family transcription factors is important for myoblast differentiation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Expression of the utrophin gene during myogenic differentiation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

AREsite: a database for the comprehensive investigation of AU-rich elements

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Down-regulation of Akt/mammalian target of rapamycin signaling pathway in response to myostatin overexpression in skeletal muscle

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

shRNA-mediated gene knockdown in skeletal muscle.

1 reference

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21 January 2018

Plasmid DNA gene therapy by electroporation: principles and recent advances

1 reference

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21 January 2018

TLR2 and TLR4 activate p38 MAPK and JNK during endurance exercise in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

AU-rich elements and the control of gene expression through regulated mRNA stability

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Molecular characterization of MARTA1, a protein interacting with the dendritic targeting element of MAP2 mRNAs

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Differentiation-induced colocalization of the KH-type splicing regulatory protein with polypyrimidine tract binding protein and the c-src pre-mRNA

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Mechanisms and functions of p38 MAPK signalling.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The p38 MAPK signaling pathway: a major regulator of skeletal muscle development

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Regulation of skeletal muscle gene expression by p38 MAP kinases.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Tristetraprolin regulates interleukin-6 expression through p38 MAPK-dependent affinity changes with mRNA 3' untranslated region

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation

1 reference

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21 January 2018

Chaperone Hsp27 modulates AUF1 proteolysis and AU-rich element-mediated mRNA degradation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The protein phosphatase calcineurin determines basal parathyroid hormone gene expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Pharmacological activation of PPARbeta/delta stimulates utrophin A expression in skeletal muscle fibers and restores sarcolemmal integrity in mature mdx mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Expression of full-length utrophin prevents muscular dystrophy in mdx mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Heregulin ameliorates the dystrophic phenotype in mdx mice

1 reference

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21 January 2018

Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

TNF-alpha regulates myogenesis and muscle regeneration by activating p38 MAPK

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Heparan sulfate mimetics modulate calpain activity during rat Soleus muscle regeneration

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT165

21 January 2018

Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA

1 reference

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21 January 2018

Identifiers

10.1093/HMG/DDT165

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

ResearchGate publication ID

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