Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes (Q45740965)

15 December 2017

title

Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes (English)

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15 December 2017

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Christian Liedtke

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Ralf Weiskirchen

object named as

Ralf Weiskirchen

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Kathrin Maedler

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Kathrin Maedler

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author name string

Hacer Sahin

1

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15 December 2017

Erawan Borkham-Kamphorst

2

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Nicole T do O

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15 December 2017

Marie-Luise Berres

4

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Michaela Kaldenbach

5

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Petra Schmitz

6

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Konrad L Streetz

9

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Christian Trautwein

11

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Hermann E Wasmuth

12

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15 December 2017

language of work or name

English

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publication date

8 January 2013

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15 December 2017

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15 December 2017

volume

57

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issue

2

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page(s)

797-805

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Mechanisms of hepatic fibrogenesis

15 December 2017

cites work

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Hepatocyte Death: A Clear and Present Danger

21 January 2018

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Functional role of chemokines in liver disease models

21 January 2018

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An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

21 January 2018

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Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans

21 January 2018

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CXCL10 promotes liver fibrosis by prevention of NK cell mediated hepatic stellate cell inactivation

21 January 2018

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CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis

21 January 2018

1 reference

Neutralization of CXCL10 accelerates liver regeneration in carbon tetrachloride-induced acute liver injury

21 January 2018

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Intrahepatic levels of CXCR3-associated chemokines correlate with liver inflammation and fibrosis in chronic hepatitis C.

21 January 2018

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Serum chemokine CXC ligand 10 (CXCL10) predicts fibrosis progression after liver transplantation for hepatitis C infection

21 January 2018

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CXCL10- a path to β-cell death

21 January 2018

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Potential role of CXCL10 in the induction of cell injury and mitochondrial dysfunction

21 January 2018

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Gamma interferon-inducible protein 10 induces HeLa cell apoptosis through a p53-dependent pathway initiated by suppression of human papillomavirus type 18 E6 and E7 expression.

21 January 2018

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Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice

21 January 2018

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Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury.

21 January 2018

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CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis.

21 January 2018

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Hepatic stellate cells secrete angiopoietin 1 that induces angiogenesis in liver fibrosis.

21 January 2018

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Caspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation

21 January 2018

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CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling.

21 January 2018

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HIV infection increases HCV-induced hepatocyte apoptosis

21 January 2018

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A T cell-dependent experimental liver injury in mice inducible by concanavalin A

21 January 2018

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IFN-gamma-inducible protein-10 (CXCL10) is hepatoprotective during acute liver injury through the induction of CXCR2 on hepatocytes

21 January 2018

1 reference

Akt induces apoptosis in neuroblastoma cells expressing a C98X vasopressin mutant following autophagy suppression.

21 January 2018

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Phosphatidylinositol 3-kinase/Akt positively regulates fas (CD95)-mediated apoptosis in epidermal Cl41 cells

21 January 2018

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The Akt proto-oncogene links Ras to Pak and cell survival signals

21 January 2018

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Functional PAK-2 knockout and replacement with a caspase cleavage-deficient mutant in mice reveals differential requirements of full-length PAK-2 and caspase-activated PAK-2p34.

21 January 2018

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CXCL10 Can Inhibit Endothelial Cell Proliferation Independently of CXCR3

21 January 2018

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TLR4 enhances TGF-beta signaling and hepatic fibrosis

21 January 2018

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Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice.

21 January 2018

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Chemokines in Liver Inflammation and Fibrosis

21 January 2018

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7 January 2021

Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice

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7 January 2021

Adenoviral CCN3/NOV gene transfer fails to mitigate liver fibrosis in an experimental bile duct ligation model because of hepatocyte apoptosis

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7 January 2021

Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes

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7 January 2021

TLR4 stresses the liver

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7 January 2021

Identifiers

DOI

10.1002/HEP.26069

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15 December 2017

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