Central leptin gene therapy blocks ovariectomy-induced adiposity (Q45862642)

17 December 2017

title

Central leptin gene therapy blocks ovariectomy-induced adiposity (English)

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17 December 2017

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Rita Torto

1

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17 December 2017

Stéphane Boghossian

2

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17 December 2017

Michael G Dube

3

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17 December 2017

Pushpa S Kalra

4

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17 December 2017

Satya P Kalra

5

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17 December 2017

publication date

1 August 2006

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17 December 2017

published in

Obesity

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17 December 2017

volume

14

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17 December 2017

issue

8

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17 December 2017

page(s)

1312-1319

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17 December 2017

Selective deletion of leptin receptor in neurons leads to obesity

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Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: effects on serum ghrelin and appetite-regulating genes

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Metabolic fuels and reproduction in female mammals

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Nutritional infertility: the role of the interconnected hypothalamic neuropeptide Y-galanin-opioid network

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Estrogen deficiency causes central leptin insensitivity and increased hypothalamic neuropeptide Y

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Leptin in reproduction.

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Increased weight gain after ovariectomy is not a consequence of leptin resistance

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Plasma leptin levels are pulsatile in adult rats: effects of gonadectomy

31 March 2020

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The obesity in bilateral ovariectomized rats is related to a decrease in the expression of leptin receptors in the brain

31 March 2020

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Is leptin a key factor which develops obesity by ovariectomy?

31 March 2020

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Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats

31 March 2020

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Regulation of serum leptin levels by gonadal function in rats

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A detailed study on the role of sex steroid milieu in determining plasma leptin concentrations in adult male and female rats

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The anorectic effect of oestradiol does not involve changes in plasma and cerebrospinal fluid leptin concentrations in the rat.

31 March 2020

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Estradiol-induced anorexia is independent of leptin and melanin-concentrating hormone

31 March 2020

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Leptin and the regulation of body weight in mammals

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Brain circuits regulating energy homeostasis

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Rhythmic, reciprocal ghrelin and leptin signaling: new insight in the development of obesity

31 March 2020

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Leptin gene expression in the brain and pituitary gland

31 March 2020

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Dose-dependent effects of central leptin gene therapy on genes that regulate body weight and appetite in the hypothalamus

31 March 2020

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Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study

31 March 2020

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Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

31 March 2020

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Congenital leptin deficiency is associated with severe early-onset obesity in humans

31 March 2020

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AAV-mediated leptin receptor installation improves energy balance and the reproductive status of obese female Koletsky rats

31 March 2020

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Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

31 March 2020

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Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy.

31 March 2020

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https://api.crossref.org/works/10.1038%2FOBY.2006.149

Evidence for the existence of distinct central appetite, energy expenditure, and ghrelin stimulation pathways as revealed by hypothalamic site-specific leptin gene therapy

31 March 2020

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Obesity and metabolic syndrome: long-term benefits of central leptin gene therapy.

31 March 2020

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Suppression of fat deposition for the life time with gene therapy

31 March 2020

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Gene-transfer technology: a preventive neurotherapy to curb obesity, ameliorate metabolic syndrome and extend life expectancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Central leptin gene therapy blocks high-fat diet-induced weight gain, hyperleptinemia, and hyperinsulinemia: increase in serum ghrelin levels

31 March 2020

1 reference

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Adipose tissue as an endocrine organ

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Increased leptin expression in the dorsal vagal complex suppresses adiposity without affecting energy intake and metabolic hormones

31 March 2020

1 reference

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Chronic leptin administration promotes lipid utilization until fat mass is greatly reduced and preserves lean mass of normal female rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Resistance to the satiety action of leptin following chronic central leptin infusion is associated with the development of leptin resistance in neuropeptide Y neurones

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia

31 March 2020

1 reference

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Adipose tissue cellularity and apoptosis after intracerebroventricular injections of leptin and 21 days of recovery in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Circumventing leptin resistance for weight control

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Increased adipose tissue in male and female estrogen receptor-alpha knockout mice

31 March 2020

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https://api.crossref.org/works/10.1038%2FOBY.2006.149

Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Leptin receptors in estrogen receptor-containing neurons of the female rat hypothalamus

31 March 2020

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https://api.crossref.org/works/10.1038%2FOBY.2006.149

Localization of neuropeptide-Y immunoreactivity in estradiol-concentrating cells in the hypothalamus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Impaired transport of leptin across the blood-brain barrier in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Obesity is associated with a decreased leptin transport across the blood-brain barrier in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

Organic cation transport in rat choroid plexus cells studied by fluorescence microscopy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2006.149

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/OBY.2006.149

1 reference

17 December 2017

1 reference

17 December 2017