Phenotype correction of Fanconi anemia group A hematopoietic stem cells using lentiviral vector (Q45869317)

17 December 2017

title

Phenotype correction of Fanconi anemia group A hematopoietic stem cells using lentiviral vector (English)

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17 December 2017

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3

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17 December 2017

author name string

Kaoru Yamada

1

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17 December 2017

Ali Ramezani

2

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17 December 2017

Wolfram Ebell

4

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17 December 2017

Fre Arwert

5

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17 December 2017

Larry W Arnold

6

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17 December 2017

Christopher E Walsh

7

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17 December 2017

publication date

1 October 2003

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17 December 2017

published in

Molecular Therapy

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17 December 2017

volume

8

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17 December 2017

issue

4

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17 December 2017

page(s)

600-610

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17 December 2017

Evidence for at least eight Fanconi anemia genes

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Positional cloning of a novel Fanconi anemia gene, FANCD2

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S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

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Biallelic inactivation of BRCA2 in Fanconi anemia

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Sequence variation in the Fanconi anemia gene FAA

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High incidence of head and neck squamous cell carcinoma in patients with Fanconi anemia.

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Cancer in Fanconi anemia, 1927-2001

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Retroviral mediated gene transfer of the Fanconi anemia complementation group C gene to hematopoietic progenitors of group C patients

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Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

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Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

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Gene therapy: trials and tribulations

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Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors

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Transduction of Human CD34+CD38- Bone Marrow and Cord Blood-Derived SCID-Repopulating Cells with Third-Generation Lentiviral Vectors

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High levels of transgene expression following transduction of long-term NOD/SCID-repopulating human cells with a modified lentiviral vector

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Lentiviral vector transduction of hematopoietic stem cells that mediate long-term reconstitution of lethally irradiated mice

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Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells

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Lentiviral vector-mediated transduction of murine CD34(-) hematopoietic stem cells

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Marking and gene expression by a lentivirus vector in transplanted human and nonhuman primate CD34(+) cells

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Antigen CD34+ marrow cells engraft lethally irradiated baboons

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Long-term in vivo expression of the human glucocerebrosidase gene in nonhuman primates after CD34+ hematopoietic cell transduction with cell-free retroviral vector preparations.

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Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

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Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

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7 January 2021

Mice with a targeted disruption of the Fanconi anemia homolog Fanca

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The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

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7 January 2021

Fanconi anemia group A and C double-mutant mice: functional evidence for a multi-protein Fanconi anemia complex.

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7 January 2021

Mobilization and collection of peripheral blood CD34+ cells from patients with Fanconi anemia

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7 January 2021

Preclinical protocol for in vivo selection of hematopoietic stem cells corrected by gene therapy in Fanconi anemia group C.

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Spontaneous functional correction of homozygous Fanconi anaemia alleles reveals novel mechanistic basis for reverse mosaicism

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7 January 2021

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

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7 January 2021

Functional correction of fanconi anemia group C hematopoietic cells by the use of a novel lentiviral vector

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Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors.

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Hematopoietic potential of stem cells isolated from murine skeletal muscle

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7 January 2021

Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells

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7 January 2021

Performance- and safety-enhanced lentiviral vectors containing the human interferon-beta scaffold attachment region and the chicken beta-globin insulator

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7 January 2021

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

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7 January 2021

Lentiviral vectors for enhanced gene expression in human hematopoietic cells

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7 January 2021

Quantitative determination of lentiviral vector particle numbers by real-time PCR

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7 January 2021

Lentivirus vector purification using anion exchange HPLC leads to improved gene transfer

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7 January 2021

A third-generation lentivirus vector with a conditional packaging system

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Identifiers

DOI

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17 December 2017

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17 December 2017